Processing, please wait...
blastall.remote -s blast.cscs.ch -p blastp -d swiss wwwtmp/sq.27500.txt -M blosum62 -K 0 -e 10.0 -F T -G def -E def -X def -v 50 -b 50 -g F |
Here are your search results:
SIB BLAST network server version 1.2.3 of June 21, 2000 Welcome to the SIB BLAST Network Service (julier) ============================================================================== Swiss Institute of Bioinformatics (SIB) Ludwig Institute for Cancer Research (LICR) Swiss Institute for Experimental Cancer Research (ISREC) ============================================================================== If results of this search are reported or published, please mention that the computation was performed at the SIB using the BLAST network service. PEPTIDE SEQUENCE DATABASES swiss SwissProt + updates 13-Oct-2000 swisstrembl SwissProt+Trembl+TrUpdates 13-Oct-2000 nr Non-redundant SP+Trembl+TrUpdates+gp+gpu 13-Oct-2000 gpupdate cumulative weekly updates of gp, currently 13-Oct-2000 shuffled SwissProt r30 shuffled in windows of 20 aa yeast S.cerevisiae translated genome ORFs NUCLEOTIDE SEQUENCE DATABASES embre * EMBL Data Library, Release 64, September 2000 embu * EmblUpdate 11-Oct-2000 embl * EMBL+EmblUpdate 11-Oct-2000 EST Database of Expressed Sequence Tags 11-Oct-2000 GSS Genome Survey Sequences 11-Oct-2000 STS Database of Sequence Tagged Sites 11-Oct-2000 nr * Non-redundant EMBL+EmblUpdate+GenBank 11-Oct-2000 repbase + Repbase, February 1996 simple Simple sequence repeats (J. Mol. Evol. 40:120, 1995) yeast S.cerevisiae genome worm C.elegans genome * The est, gss, and sts divisions of EMBL are excluded from these databases. + Contains sequences from the files humrep.ref, invrep.ref, mamrep.ref, plnrep.ref, rodrep.ref, and vertrep.ref from repbase. ============================================================================ The BLAST Network Service uses a server developed at SIB and the NCBI BLAST 2 software. For problems regarding this site, please contact one of the following persons: - problems with the programs: Christian Iseli (chris@cmpteam4.unil.ch) - problems with the databases: Victor Jongeneel (Victor.Jongeneel@isb-sib.ch) ============================================================================ BLASTP 2.0.12 [Apr-21-2000] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= sp|P35348|A1AA_HUMAN (ADRA1A..)ALPHA-1A ADRENERGIC (466 letters) Database: swiss 88,757 sequences; 32,294,092 total letters Searching...................................................done
Score E Sequences producing significant alignments: (bits) Value N sp|P35348|A1AA_HUMAN (ADRA1A..)ALPHA-1A ADRENERGIC RECEPTOR... 1035 0.0 2 sp|O02824|A1AA_RABIT (ADRA1A..)ALPHA-1A ADRENERGIC RECEPTOR... 980 0.0 2 sp|P43140|A1AA_RAT (ADRA1A..)ALPHA-1A ADRENERGIC RECEPTOR (... 976 0.0 2 sp|P18130|A1AA_BOVIN (ADRA1A..)ALPHA-1A ADRENERGIC RECEPTOR... 966 0.0 2 sp|O77621|A1AA_CANFA (ADRA1A..)ALPHA-1A ADRENERGIC RECEPTOR... 589 e-180 2 sp|Q91175|A1AA_ORYLA ALPHA-1A ADRENERGIC RECEPTOR (MAR1).[O... 388 e-164 4 sp|P15823|A1AB_RAT (ADRA1B)ALPHA-1B ADRENERGIC RECEPTOR (AL... 340 e-138 2 sp|P18841|A1AB_MESAU (ADRA1B)ALPHA-1B ADRENERGIC RECEPTOR (... 340 e-138 2 sp|P35368|A1AB_HUMAN (ADRA1B)ALPHA-1B ADRENERGIC RECEPTOR (... 339 e-138 2 sp|O02666|A1AD_RABIT (ADRA1D)ALPHA-1D ADRENERGIC RECEPTOR (... 324 e-138 2 sp|P97717|A1AB_MOUSE (ADRA1B)ALPHA-1B ADRENERGIC RECEPTOR (... 337 e-137 2 sp|P25100|A1AD_HUMAN (ADRA1D..)ALPHA-1D ADRENERGIC RECEPTOR... 321 e-136 2 sp|P23944|A1AD_RAT (ADRA1D..)ALPHA-1D ADRENERGIC RECEPTOR (... 319 e-135 2 sp|P97714|A1AD_MOUSE (ADRA1D..)ALPHA-1D ADRENERGIC RECEPTOR... 316 e-134 2 sp|P11615|A1AB_CANFA (ADRA1B..)ALPHA-1B ADRENERGIC RECEPTOR... 290 e-124 2 sp|Q93126|GREC_BALAM PROBABLE G PROTEIN-COUPLED RECEPTOR.[B... 151 2e-69 4 sp|O77408|OAR1_LYMST OCTOPAMINE RECEPTOR 1 (OA1).[Lymnaea s... 149 2e-66 5 sp|Q25322|OAR2_LOCMI (GCR2)PUTATIVE TYRAMINE RECEPTOR 2 (TY... 130 2e-64 4 sp|Q25321|OAR1_LOCMI (GCR1)TYRAMINE RECEPTOR 1 (TYR-LOC1).[... 130 2e-64 4 sp|Q17232|OAR_BOMMO OCTOPAMINE RECEPTOR.[Bombyx mori] 130 2e-64 3 sp|Q25188|OAR_HELVI OCTOPAMINE RECEPTOR.[Heliothis virescens] 131 4e-63 3 sp|P22270|OAR_DROME (OCR..)TYRAMINE/OCTOPAMINE RECEPTOR PRE... 132 2e-62 3 sp|Q24563|DOP2_DROME (DOPR2..)DOPAMINE RECEPTOR 2.[Drosophi... 84 1e-61 5 sp|Q25414|5HT_LYMST 5-HYDROXYTRYPTAMINE RECEPTOR (5-HT RECE... 101 4e-60 4 sp|P32304|5H7_MOUSE (HTR7)5-HYDROXYTRYPTAMINE 7 RECEPTOR (5... 116 2e-58 5 sp|P30939|5H1F_HUMAN (HTR1F..)5-HYDROXYTRYPTAMINE 1F RECEPT... 143 2e-58 2 sp|O08890|5H1F_CAVPO (HTR1F)5-HYDROXYTRYPTAMINE 1F RECEPTOR... 144 6e-58 2 sp|P79748|5H1D_FUGRU 5-HYDROXYTRYPTAMINE 1D RECEPTOR (5-HT-... 120 2e-57 3 sp|P49144|5H1B_RABIT (HTR1B)5-HYDROXYTRYPTAMINE 1B RECEPTOR... 130 2e-57 4 sp|Q02284|5H1F_MOUSE (HTR1F..)5-HYDROXYTRYPTAMINE 1F RECEPT... 143 3e-57 2 sp|P25102|HH2R_RAT (HRH2)HISTAMINE H2 RECEPTOR (GASTRIC REC... 137 3e-57 3 sp|P19327|5H1A_RAT (HTR1A..)5-HYDROXYTRYPTAMINE 1A RECEPTOR... 133 3e-57 4 sp|P08908|5H1A_HUMAN (HTR1A)5-HYDROXYTRYPTAMINE 1A RECEPTOR... 133 3e-57 4 sp|P28334|5H1B_MOUSE (HTR1B..)5-HYDROXYTRYPTAMINE 1B RECEPT... 129 4e-57 4 sp|Q18775|YYI3_CAEEL (C52B11.3)PROBABLE G PROTEIN-COUPLED R... 93 4e-57 5 sp|Q64264|5H1A_MOUSE (HTR1A)5-HYDROXYTRYPTAMINE 1A RECEPTOR... 133 5e-57 4 sp|O42385|5H1A_FUGRU 5-HYDROXYTRYPTAMINE 1A-ALPHA RECEPTOR ... 127 5e-57 4 sp|P28564|5H1B_RAT (HTR1B..)5-HYDROXYTRYPTAMINE 1B RECEPTOR... 128 7e-57 4 sp|P28222|5H1B_HUMAN (HTR1B..)5-HYDROXYTRYPTAMINE 1B RECEPT... 128 2e-56 4 sp|P97292|HH2R_MOUSE (HRH2)HISTAMINE H2 RECEPTOR (GASTRIC R... 136 2e-56 3 sp|P30940|5H1F_RAT (HTR1F..)5-HYDROXYTRYPTAMINE 1F RECEPTOR... 140 3e-56 2 sp|Q91559|5H7_XENLA (5HT7)5-HYDROXYTRYPTAMINE 7 RECEPTOR (5... 112 4e-56 5 sp|P25021|HH2R_HUMAN (HRH2)HISTAMINE H2 RECEPTOR (GASTRIC R... 137 4e-56 3 sp|P11614|5H1D_CANFA (HTR1D..)5-HYDROXYTRYPTAMINE 1D RECEPT... 131 6e-56 4 sp|P46636|5H1B_CRIGR (HTR1B)5-HYDROXYTRYPTAMINE 1B RECEPTOR... 129 6e-56 4 sp|P28286|5HTB_DROME (5-HT1B..)5-HYDROXYTRYPTAMINE RECEPTOR... 97 9e-56 4 sp|P18089|A2AB_HUMAN (ADRA2B)ALPHA-2B ADRENERGIC RECEPTOR (... 119 1e-55 4 sp|P35404|5H1B_DIDMA 5-HYDROXYTRYPTAMINE 1B RECEPTOR (5-HT-... 149 1e-55 3 sp|P50407|5H7_CAVPO (HTR7)5-HYDROXYTRYPTAMINE 7 RECEPTOR (5... 115 1e-55 5 sp|P56496|5H1B_SPAEH (HTR1B..)5-HYDROXYTRYPTAMINE 1B RECEPT... 126 2e-55 4 >sp|P35348|A1AA_HUMAN (ADRA1A..)ALPHA-1A ADRENERGIC RECEPTOR (ALPHA 1A-ADRENOCEPTOR) (ALPHA-1C ADRENERGIC RECEPTOR).[Homo sapiens] Length = 466 Score = 65.6 bits (134), Expect(2) = 0.0 Identities = 26/26 (100%), Positives = 26/26 (100%) Query: 1 MVFLSGNASDSSNCTQPPAPVNISKA 26 MVFLSGNASDSSNCTQPPAPVNISKA Sbjct: 1 MVFLSGNASDSSNCTQPPAPVNISKA 26 Score = 1035 bits (2205), Expect(2) = 0.0 Identities = 417/417 (100%), Positives = 417/417 (100%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC Sbjct: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPA 169 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPA Sbjct: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPA 169 Query: 170 PEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDS 229 PEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDS Sbjct: 170 PEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDS 229 Query: 230 EQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFF 289 EQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFF Sbjct: 230 EQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFF 289 Query: 290 LVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRK 349 LVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRK Sbjct: 290 LVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRK 349 Query: 350 QSSKHALGYTLHPPSQAVEGQHKDMVRIPVGSRETFYRISKTDGVCEWKFFSSMPRGSAR 409 QSSKHALGYTLHPPSQAVEGQHKDMVRIPVGSRETFYRISKTDGVCEWKFFSSMPRGSAR Sbjct: 350 QSSKHALGYTLHPPSQAVEGQHKDMVRIPVGSRETFYRISKTDGVCEWKFFSSMPRGSAR 409 Query: 410 ITVSKDQSSCTTARVRSKSFLQVCCCVGPSTPSLDKNHQVPTIKVHTISLSENGEEV 466 ITVSKDQSSCTTARVRSKSFLQVCCCVGPSTPSLDKNHQVPTIKVHTISLSENGEEV Sbjct: 410 ITVSKDQSSCTTARVRSKSFLQVCCCVGPSTPSLDKNHQVPTIKVHTISLSENGEEV 466 >sp|O02824|A1AA_RABIT (ADRA1A..)ALPHA-1A ADRENERGIC RECEPTOR (ALPHA 1A-ADRENOCEPTOR) (ALPHA-1C ADRENERGIC RECEPTOR).[Oryctolagus cuniculus] Length = 466 Score = 63.3 bits (129), Expect(2) = 0.0 Identities = 25/26 (96%), Positives = 25/26 (96%) Query: 1 MVFLSGNASDSSNCTQPPAPVNISKA 26 MVFLSGNASDSSNCT PPAPVNISKA Sbjct: 1 MVFLSGNASDSSNCTHPPAPVNISKA 26 Score = 980 bits (2088), Expect(2) = 0.0 Identities = 390/417 (93%), Positives = 404/417 (96%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFE+LGYWAFGRVFCNIWAAVDVLC Sbjct: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLC 109 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPA 169 CTASI+ LC+ISIDRYIGVSYPLRYPTIVTQRRGL ALLCVWA SLVIS+GPLFGWRQPA Sbjct: 110 CTASIISLCVISIDRYIGVSYPLRYPTIVTQRRGLRALLCVWAFSLVISVGPLFGWRQPA 169 Query: 170 PEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDS 229 P+DETICQINEEPGYVLFSALGSFY+PL IIL MYCRVYVVAKRESRGLKSGLKTDKSDS Sbjct: 170 PDDETICQINEEPGYVLFSALGSFYVPLTIILAMYCRVYVVAKRESRGLKSGLKTDKSDS 229 Query: 230 EQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFF 289 EQVTLRIHRKNAPAGGSG+ASAK KTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFF Sbjct: 230 EQVTLRIHRKNAPAGGSGVASAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFF 289 Query: 290 LVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRK 349 LVMPIGSFFPDFKP ETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL+IQCL RK Sbjct: 290 LVMPIGSFFPDFKPPETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLKIQCLRRK 349 Query: 350 QSSKHALGYTLHPPSQAVEGQHKDMVRIPVGSRETFYRISKTDGVCEWKFFSSMPRGSAR 409 QSSKHALGYTLH PSQA+EGQHKDMVRIPVGS ETFY+ISKTDGVCEWKFFSSMPRGSAR Sbjct: 350 QSSKHALGYTLHAPSQALEGQHKDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPRGSAR 409 Query: 410 ITVSKDQSSCTTARVRSKSFLQVCCCVGPSTPSLDKNHQVPTIKVHTISLSENGEEV 466 ITV KDQS+CTTARVRSKSFLQVCCCVGPSTP+ +NHQVPTIK+HTISLSENGEEV Sbjct: 410 ITVPKDQSACTTARVRSKSFLQVCCCVGPSTPNPGENHQVPTIKIHTISLSENGEEV 466 >sp|P43140|A1AA_RAT (ADRA1A..)ALPHA-1A ADRENERGIC RECEPTOR (ALPHA 1A-ADRENOCEPTOR) (ALPHA-1C ADRENERGIC RECEPTOR).[Rattus norvegicus] Length = 466 Score = 53.0 bits (107), Expect(2) = 0.0 Identities = 21/26 (80%), Positives = 22/26 (83%) Query: 1 MVFLSGNASDSSNCTQPPAPVNISKA 26 MV LS NAS+ SNCT PPAPVNISKA Sbjct: 1 MVLLSENASEGSNCTHPPAPVNISKA 26 Score = 976 bits (2079), Expect(2) = 0.0 Identities = 389/417 (93%), Positives = 403/417 (96%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFE+LGYWAFGRVFCNIWAAVDVLC Sbjct: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLC 109 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPA 169 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRG+ ALLCVW LSLVISIGPLFGWRQPA Sbjct: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGVRALLCVWVLSLVISIGPLFGWRQPA 169 Query: 170 PEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDS 229 PEDETICQINEEPGYVLFSALGSFY+PLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDS Sbjct: 170 PEDETICQINEEPGYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDS 229 Query: 230 EQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFF 289 EQVTLRIHRKN PA G G++SAK KTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFF Sbjct: 230 EQVTLRIHRKNVPAEGGGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFF 289 Query: 290 LVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRK 349 LVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCL R+ Sbjct: 290 LVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRR 349 Query: 350 QSSKHALGYTLHPPSQAVEGQHKDMVRIPVGSRETFYRISKTDGVCEWKFFSSMPRGSAR 409 QSSKHALGYTLHPPSQA+EGQH+DMVRIPVGS ETFY+ISKTDGVCEWKFFSSMP+GSAR Sbjct: 350 QSSKHALGYTLHPPSQALEGQHRDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPQGSAR 409 Query: 410 ITVSKDQSSCTTARVRSKSFLQVCCCVGPSTPSLDKNHQVPTIKVHTISLSENGEEV 466 ITV KDQS+CTTARVRSKSFLQVCCCVG S P ++NHQVPTIK+HTISL ENGEEV Sbjct: 410 ITVPKDQSACTTARVRSKSFLQVCCCVGSSAPRPEENHQVPTIKIHTISLGENGEEV 466 >sp|P18130|A1AA_BOVIN (ADRA1A..)ALPHA-1A ADRENERGIC RECEPTOR (ALPHA 1A-ADRENOCEPTOR) (ALPHA-1C ADRENERGIC RECEPTOR).[Bos taurus] Length = 466 Score = 60.9 bits (124), Expect(2) = 0.0 Identities = 24/26 (92%), Positives = 24/26 (92%) Query: 1 MVFLSGNASDSSNCTQPPAPVNISKA 26 MVFLSGNASDSSNCT PP PVNISKA Sbjct: 1 MVFLSGNASDSSNCTHPPPPVNISKA 26 Score = 966 bits (2058), Expect(2) = 0.0 Identities = 382/417 (91%), Positives = 400/417 (95%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFE+LGYWAFGRVFCN+WAAVDVLC Sbjct: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNVWAAVDVLC 109 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPA 169 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQ+RGLMALLCVWALSLVISIGPLFGWRQPA Sbjct: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQKRGLMALLCVWALSLVISIGPLFGWRQPA 169 Query: 170 PEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDS 229 PEDETICQINEEPGYVLFSALGSFY+PL IILVMYCRVYVVAKRESRGLKSGLKTDKSDS Sbjct: 170 PEDETICQINEEPGYVLFSALGSFYVPLTIILVMYCRVYVVAKRESRGLKSGLKTDKSDS 229 Query: 230 EQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFF 289 EQVTLRIHRKNA GGSG+ SAK KTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFF Sbjct: 230 EQVTLRIHRKNAQVGGSGVTSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFF 289 Query: 290 LVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRK 349 LVMPIGSFFPDF+PSETVFKI FWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCL RK Sbjct: 290 LVMPIGSFFPDFRPSETVFKIAFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRK 349 Query: 350 QSSKHALGYTLHPPSQAVEGQHKDMVRIPVGSRETFYRISKTDGVCEWKFFSSMPRGSAR 409 QSSKH LGYTLH PS +EGQHKD+VRIPVGS ETFY+ISKTDGVCEWK FSS+PRGSAR Sbjct: 350 QSSKHTLGYTLHAPSHVLEGQHKDLVRIPVGSAETFYKISKTDGVCEWKIFSSLPRGSAR 409 Query: 410 ITVSKDQSSCTTARVRSKSFLQVCCCVGPSTPSLDKNHQVPTIKVHTISLSENGEEV 466 + V++D S+CTTARVRSKSFLQVCCC+GPSTPS +NHQ+PTIK+HTISLSENGEEV Sbjct: 410 MAVARDPSACTTARVRSKSFLQVCCCLGPSTPSHGENHQIPTIKIHTISLSENGEEV 466 >sp|O77621|A1AA_CANFA (ADRA1A..)ALPHA-1A ADRENERGIC RECEPTOR (ALPHA 1A-ADRENOCEPTOR) (ALPHA-1C ADRENERGIC RECEPTOR) (FRAGMENT).[Canis familiaris] Length = 295 Score = 63.3 bits (129), Expect(2) = e-180 Identities = 25/26 (96%), Positives = 25/26 (96%) Query: 1 MVFLSGNASDSSNCTQPPAPVNISKA 26 MVFLSGNASDSSNCT PPAPVNISKA Sbjct: 1 MVFLSGNASDSSNCTHPPAPVNISKA 26 Score = 589 bits (1252), Expect(2) = e-180 Identities = 236/246 (95%), Positives = 242/246 (97%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFE+LGYWAFGRVFCNIWAAVDVLC Sbjct: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLC 109 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPA 169 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQ+RGLMALLCVWALSLVISIGPLFGWRQPA Sbjct: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQKRGLMALLCVWALSLVISIGPLFGWRQPA 169 Query: 170 PEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDS 229 PEDETICQI EEPGYVLFSALGSFY+PL IILVMYCRVYVVAKRESRGLKSGLKTDKSDS Sbjct: 170 PEDETICQITEEPGYVLFSALGSFYVPLTIILVMYCRVYVVAKRESRGLKSGLKTDKSDS 229 Query: 230 EQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFF 289 EQVTLRIHRKNAP GG+G++SAK KTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFF Sbjct: 230 EQVTLRIHRKNAPVGGTGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFF 289 Query: 290 LVMPIG 295 LVMPIG Sbjct: 290 LVMPIG 295 >sp|Q91175|A1AA_ORYLA ALPHA-1A ADRENERGIC RECEPTOR (MAR1).[Oryzias latipes] Length = 470 Score = 388 bits (824), Expect(4) = e-164 Identities = 148/191 (77%), Positives = 173/191 (90%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 SV CHRHL +VT+Y+IVNLAVADLLL+STVLPFSAIFE+L W FGRVFCNIWAAVDVLC Sbjct: 50 SVVCHRHLQTVTYYFIVNLAVADLLLSSTVLPFSAIFEILDRWVFGRVFCNIWAAVDVLC 109 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPA 169 CTASIM LC+IS+DRYIGVSYPLRYP I+T+RR L+A++ +W LS++ISIGPLFGW++PA Sbjct: 110 CTASIMSLCVISVDRYIGVSYPLRYPAIMTKRRALLAVMLLWVLSVIISIGPLFGWKEPA 169 Query: 170 PEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDS 229 PEDET+C+I EEPGY +FSA+GSFYLPLAIIL MYCRVYVVA++ESRGLK G K +KSDS Sbjct: 170 PEDETVCKITEEPGYAIFSAVGSFYLPLAIILAMYCRVYVVAQKESRGLKEGQKIEKSDS 229 Query: 230 EQVTLRIHRKN 240 EQV LR+HR N Sbjct: 230 EQVILRMHRGN 240 Score = 203 bits (428), Expect(4) = e-164 Identities = 76/103 (73%), Positives = 90/103 (86%) Query: 252 KTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIV 311 +++THF++RLLKFSREKKAAKTLGIVVGCFVLCWLPFFLV+PIGS FP ++PS+TVFKI Sbjct: 250 RSRTHFALRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVLPIGSIFPAYRPSDTVFKIT 309 Query: 312 FWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKH 354 FWLGY NSCINPIIY CS+QEFKKAFQ++L + CL + H Sbjct: 310 FWLGYFNSCINPIIYLCSNQEFKKAFQSLLGVHCLRMTPRAHH 352 Score = 22.5 bits (42), Expect(4) = e-164 Identities = 6/15 (40%), Positives = 11/15 (73%) Query: 422 ARVRSKSFLQVCCCV 436 A++ +KS + CCC+ Sbjct: 423 AKLCNKSLHRTCCCI 437 Score = 33.8 bits (66), Expect(4) = e-164 Identities = 12/18 (66%), Positives = 15/18 (82%) Query: 449 VPTIKVHTISLSENGEEV 466 +PTIK+H +SLSE GE V Sbjct: 453 LPTIKIHQLSLSEKGESV 470 >sp|P15823|A1AB_RAT (ADRA1B)ALPHA-1B ADRENERGIC RECEPTOR (ALPHA 1B-ADRENOCEPTOR).[Rattus norvegicus] Length = 515 Score = 340 bits (721), Expect(2) = e-138 Identities = 129/191 (67%), Positives = 162/191 (84%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 SVAC+RHL + T+Y+IVNLA+ADLLL+ TVLPFSA EVLGYW GR+FC+IWAAVDVLC Sbjct: 69 SVACNRHLRTPTNYFIVNLAIADLLLSFTVLPFSATLEVLGYWVLGRIFCDIWAAVDVLC 128 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPA 169 CTASI+ LC ISIDRYIGV Y L+YPT+VT+R+ ++ALL VW LS VISIGPL GW++PA Sbjct: 129 CTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWKEPA 188 Query: 170 PEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDS 229 P D+ C + EEP Y LFS+LGSFY+PLA+ILVMYCRVY+VAKR ++ L++G+ + S+S Sbjct: 189 PNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNS 248 Query: 230 EQVTLRIHRKN 240 +++TLRIH KN Sbjct: 249 KELTLRIHSKN 259 Score = 173 bits (365), Expect(2) = e-138 Identities = 62/92 (67%), Positives = 76/92 (82%) Query: 254 KTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFW 313 ++ +V+L KFSREKKAAKTLGIVVG F+LCWLPFF+ +P+GS F KP + VFK+VFW Sbjct: 276 RSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFW 335 Query: 314 LGYLNSCINPIIYPCSSQEFKKAFQNVLRIQC 345 LGY NSC+NPIIYPCSS+EFK+AF +L QC Sbjct: 336 LGYFNSCLNPIIYPCSSKEFKRAFMRILGCQC 367 >sp|P18841|A1AB_MESAU (ADRA1B)ALPHA-1B ADRENERGIC RECEPTOR (ALPHA 1B-ADRENOCEPTOR).[Mesocricetus auratus] Length = 515 Score = 340 bits (721), Expect(2) = e-138 Identities = 129/191 (67%), Positives = 162/191 (84%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 SVAC+RHL + T+Y+IVNLA+ADLLL+ TVLPFSA EVLGYW GR+FC+IWAAVDVLC Sbjct: 69 SVACNRHLRTPTNYFIVNLAIADLLLSFTVLPFSATLEVLGYWVLGRIFCDIWAAVDVLC 128 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPA 169 CTASI+ LC ISIDRYIGV Y L+YPT+VT+R+ ++ALL VW LS VISIGPL GW++PA Sbjct: 129 CTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWKEPA 188 Query: 170 PEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDS 229 P D+ C + EEP Y LFS+LGSFY+PLA+ILVMYCRVY+VAKR ++ L++G+ + S+S Sbjct: 189 PNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNS 248 Query: 230 EQVTLRIHRKN 240 +++TLRIH KN Sbjct: 249 KELTLRIHSKN 259 Score = 173 bits (365), Expect(2) = e-138 Identities = 62/92 (67%), Positives = 76/92 (82%) Query: 254 KTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFW 313 ++ +V+L KFSREKKAAKTLGIVVG F+LCWLPFF+ +P+GS F KP + VFK+VFW Sbjct: 276 RSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFW 335 Query: 314 LGYLNSCINPIIYPCSSQEFKKAFQNVLRIQC 345 LGY NSC+NPIIYPCSS+EFK+AF +L QC Sbjct: 336 LGYFNSCLNPIIYPCSSKEFKRAFMRILGCQC 367 >sp|P35368|A1AB_HUMAN (ADRA1B)ALPHA-1B ADRENERGIC RECEPTOR (ALPHA 1B-ADRENOCEPTOR).[Homo sapiens] Length = 519 Score = 339 bits (719), Expect(2) = e-138 Identities = 129/191 (67%), Positives = 162/191 (84%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 SVAC+RHL + T+Y+IVNLA+ADLLL+ TVLPFSA EVLGYW GR+FC+IWAAVDVLC Sbjct: 69 SVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLC 128 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPA 169 CTASI+ LC ISIDRYIGV Y L+YPT+VT+R+ ++ALL VW LS VISIGPL GW++PA Sbjct: 129 CTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWKEPA 188 Query: 170 PEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDS 229 P D+ C + EEP Y LFS+LGSFY+PLA+ILVMYCRVY+VAKR ++ L++G+ + S+S Sbjct: 189 PNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNS 248 Query: 230 EQVTLRIHRKN 240 +++TLRIH KN Sbjct: 249 KELTLRIHSKN 259 Score = 174 bits (366), Expect(2) = e-138 Identities = 63/97 (64%), Positives = 79/97 (80%) Query: 254 KTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFW 313 ++ +V+L KFSREKKAAKTLGIVVG F+LCWLPFF+ +P+GS F KP + VFK+VFW Sbjct: 276 RSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFW 335 Query: 314 LGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQ 350 LGY NSC+NPIIYPCSS+EFK+AF +L QC R++ Sbjct: 336 LGYFNSCLNPIIYPCSSKEFKRAFVRILGCQCRGRRR 372 >sp|O02666|A1AD_RABIT (ADRA1D)ALPHA-1D ADRENERGIC RECEPTOR (ALPHA 1D-ADRENOCEPTOR).[Oryctolagus cuniculus] Length = 576 Score = 324 bits (686), Expect(2) = e-138 Identities = 120/198 (60%), Positives = 160/198 (80%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 SVAC+RHL +VT+Y+IVNLAVADLLL++TVLPFSA EVLG+WAFGR FC++WAAVDVLC Sbjct: 125 SVACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEVLGFWAFGRAFCDVWAAVDVLC 184 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPA 169 CTASI+ LC IS+DRY+GV + L+YP I+T+R+ L +WA++LV+S+GPL GW++P Sbjct: 185 CTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWAVALVVSMGPLLGWKEPV 244 Query: 170 PEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDS 229 P DE C I EE GY +FS+L SFYLP+A+I+VMYCRVYVVA+ +R L++G+K ++ + Sbjct: 245 PPDERFCGITEEVGYAVFSSLCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKA 304 Query: 230 EQVTLRIHRKNAPAGGSG 247 +V LRIH + A +G G Sbjct: 305 SEVVLRIHCRGAASGADG 322 Score = 188 bits (397), Expect(2) = e-138 Identities = 76/130 (58%), Positives = 90/130 (68%) Query: 244 GGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKP 303 G G ++ SVRLLKFSREKKAAKTL IVVG FVLCW PFF V+P+GS FP KP Sbjct: 325 GTRGAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKP 384 Query: 304 SETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTLHPP 363 SE VFK++FWLGY NSC+NP+IYPCSS+EFK+AF +LR QC R++ Y H Sbjct: 385 SEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRRRRPLWRVYGHHWR 444 Query: 364 SQAVEGQHKD 373 + A G H D Sbjct: 445 ASAGGGPHPD 454 >sp|P97717|A1AB_MOUSE (ADRA1B)ALPHA-1B ADRENERGIC RECEPTOR (ALPHA 1B-ADRENOCEPTOR).[Mus musculus] Length = 514 Score = 337 bits (714), Expect(2) = e-137 Identities = 128/191 (67%), Positives = 161/191 (84%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 SVAC+RHL + T+Y+IVNLA+ADLLL+ T LPFSA EVLGYW GR+FC+IWAAVDVLC Sbjct: 68 SVACNRHLRTPTNYFIVNLAIADLLLSFTDLPFSATLEVLGYWVLGRIFCDIWAAVDVLC 127 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPA 169 CTASI+ LC ISIDRYIGV Y L+YPT+VT+R+ ++ALL VW LS VISIGPL GW++PA Sbjct: 128 CTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWKEPA 187 Query: 170 PEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDS 229 P D+ C + EEP Y LFS+LGSFY+PLA+ILVMYCRVY+VAKR ++ L++G+ + S+S Sbjct: 188 PNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNS 247 Query: 230 EQVTLRIHRKN 240 +++TLRIH KN Sbjct: 248 KELTLRIHSKN 258 Score = 173 bits (365), Expect(2) = e-137 Identities = 62/92 (67%), Positives = 76/92 (82%) Query: 254 KTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFW 313 ++ +V+L KFSREKKAAKTLGIVVG F+LCWLPFF+ +P+GS F KP + VFK+VFW Sbjct: 275 RSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFW 334 Query: 314 LGYLNSCINPIIYPCSSQEFKKAFQNVLRIQC 345 LGY NSC+NPIIYPCSS+EFK+AF +L QC Sbjct: 335 LGYFNSCLNPIIYPCSSKEFKRAFMRILGCQC 366 >sp|P25100|A1AD_HUMAN (ADRA1D..)ALPHA-1D ADRENERGIC RECEPTOR (ALPHA 1D-ADRENOCEPTOR) (ALPHA-1A ADRENERGIC RECEPTOR).[Homo sapiens] Length = 572 Score = 321 bits (681), Expect(2) = e-136 Identities = 118/198 (59%), Positives = 158/198 (79%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 SVAC+RHL +VT+Y+IVNLAVADLLL++TVLPFSA EVLG+WAFGR FC++WAAVDVLC Sbjct: 120 SVACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEVLGFWAFGRAFCDVWAAVDVLC 179 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPA 169 CTASI+ LC IS+DRY+GV + L+YP I+T+R+ L +W ++LV+S+GPL GW++P Sbjct: 180 CTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWVVALVVSVGPLLGWKEPV 239 Query: 170 PEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDS 229 P DE C I EE GY +FS++ SFYLP+A+I+VMYCRVYVVA+ +R L++G+K ++ + Sbjct: 240 PPDERFCGITEEAGYAVFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKA 299 Query: 230 EQVTLRIHRKNAPAGGSG 247 +V LRIH + A G G Sbjct: 300 SEVVLRIHCRGAATGADG 317 Score = 184 bits (387), Expect(2) = e-136 Identities = 68/97 (70%), Positives = 81/97 (83%) Query: 254 KTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFW 313 ++ SVRLLKFSREKKAAKTL IVVG FVLCW PFF V+P+GS FP KPSE VFK++FW Sbjct: 330 RSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVFKVIFW 389 Query: 314 LGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQ 350 LGY NSC+NP+IYPCSS+EFK+AF +LR QC R++ Sbjct: 390 LGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRR 426 >sp|P23944|A1AD_RAT (ADRA1D..)ALPHA-1D ADRENERGIC RECEPTOR (ALPHA 1D-ADRENOCEPTOR) (ALPHA-1A ADRENERGIC RECEPTOR) (RA42).[Rattus norvegicus] Length = 561 Score = 319 bits (675), Expect(2) = e-135 Identities = 118/211 (55%), Positives = 161/211 (75%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 SVAC+RHL +VT+Y+IVNLAVADLLL++ VLPFSA EVLG+WAFGR FC++WAAVDVLC Sbjct: 114 SVACNRHLQTVTNYFIVNLAVADLLLSAAVLPFSATMEVLGFWAFGRTFCDVWAAVDVLC 173 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPA 169 CTASI+ LC IS+DRY+GV + L+YP I+T+R+ L +WA++LV+S+GPL GW++P Sbjct: 174 CTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWAVALVVSVGPLLGWKEPV 233 Query: 170 PEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDS 229 P DE C I EE GY +FS++ SFYLP+A+I+VMYCRVYVVA+ +R L++G+K + + Sbjct: 234 PPDERFCGITEEVGYAIFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGIKREPGKA 293 Query: 230 EQVTLRIHRKNAPAGGSGMASAKTKTHFSVR 260 +V LRIH + A G ++ ++R Sbjct: 294 SEVVLRIHCRGAATSAKGYPGTQSSKGHTLR 324 Score = 184 bits (387), Expect(2) = e-135 Identities = 68/97 (70%), Positives = 81/97 (83%) Query: 254 KTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFW 313 ++ SVRLLKFSREKKAAKTL IVVG FVLCW PFF V+P+GS FP KPSE VFK++FW Sbjct: 324 RSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVFKVIFW 383 Query: 314 LGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQ 350 LGY NSC+NP+IYPCSS+EFK+AF +LR QC R++ Sbjct: 384 LGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRR 420 >sp|P97714|A1AD_MOUSE (ADRA1D..)ALPHA-1D ADRENERGIC RECEPTOR (ALPHA 1D-ADRENOCEPTOR) (ALPHA-1A ADRENERGIC RECEPTOR).[Mus musculus] Length = 562 Score = 316 bits (669), Expect(2) = e-134 Identities = 117/211 (55%), Positives = 160/211 (75%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 SVAC+RHL +VT+Y+IVNLAVADLLL++ VLPFSA EVLG+W FGR FC++WAAVDVLC Sbjct: 114 SVACNRHLQTVTNYFIVNLAVADLLLSAAVLPFSATMEVLGFWPFGRTFCDVWAAVDVLC 173 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPA 169 CTASI+ LC IS+DRY+GV + L+YP I+T+R+ L +WA++LV+S+GPL GW++P Sbjct: 174 CTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWAVALVVSVGPLLGWKEPV 233 Query: 170 PEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDS 229 P DE C I EE GY +FS++ SFYLP+A+I+VMYCRVYVVA+ +R L++G+K + + Sbjct: 234 PPDERFCGITEEVGYAIFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGIKREPGKA 293 Query: 230 EQVTLRIHRKNAPAGGSGMASAKTKTHFSVR 260 +V LRIH + A G ++ ++R Sbjct: 294 SEVVLRIHCRGAATSAKGNPGTQSSKGHTLR 324 Score = 184 bits (387), Expect(2) = e-134 Identities = 68/97 (70%), Positives = 81/97 (83%) Query: 254 KTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFW 313 ++ SVRLLKFSREKKAAKTL IVVG FVLCW PFF V+P+GS FP KPSE VFK++FW Sbjct: 324 RSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVFKVIFW 383 Query: 314 LGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQ 350 LGY NSC+NP+IYPCSS+EFK+AF +LR QC R++ Sbjct: 384 LGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRR 420 >sp|P11615|A1AB_CANFA (ADRA1B..)ALPHA-1B ADRENERGIC RECEPTOR (ALPHA 1B-ADRENOCEPTOR) (FRAGMENT).[Canis familiaris] Length = 417 Score = 290 bits (614), Expect(2) = e-124 Identities = 109/162 (67%), Positives = 136/162 (83%) Query: 79 VLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIV 138 VLPFSA EVLGYW GR+FC+IWAAVDVLCCTASI+ LC ISIDRYIGV Y L+YPT+V Sbjct: 1 VLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLV 60 Query: 139 TQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYLPLA 198 T+R+ ++ALL VW LS VISIGPL GW++PAP D+ C + EEP Y LFS+LGSFY+PLA Sbjct: 61 TRRKAILALLGVWVLSTVISIGPLLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLA 120 Query: 199 IILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN 240 +ILVMYCRVY+VAKR ++ L++G+ + S+S+++TLRIH KN Sbjct: 121 VILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKN 162 Score = 174 bits (366), Expect(2) = e-124 Identities = 63/97 (64%), Positives = 79/97 (80%) Query: 254 KTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFW 313 ++ +V+L KFSREKKAAKTLGIVVG F+LCWLPFF+ +P+GS F KP + VFK+VFW Sbjct: 179 RSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFW 238 Query: 314 LGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQ 350 LGY NSC+NPIIYPCSS+EFK+AF +L QC R++ Sbjct: 239 LGYFNSCLNPIIYPCSSKEFKRAFVRILGCQCRGRRR 275 >sp|Q93126|GREC_BALAM PROBABLE G PROTEIN-COUPLED RECEPTOR.[Balanus amphitrite] Length = 476 Score = 151 bits (318), Expect(4) = 2e-69 Identities = 59/116 (50%), Positives = 79/116 (67%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 +V H L +VT+ +IV+LA ADLL+ VLPFSA EVL W +G V+C++W AVDV Sbjct: 57 AVFVHSKLRTVTNLFIVSLACADLLVGMLVLPFSATLEVLDVWLYGDVWCSVWLAVDVWM 116 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGW 165 CT+SI+ LC IS+DRY+ VS P+ YP++++ RR + VW LS VI PL GW Sbjct: 117 CTSSILNLCAISLDRYLAVSQPISYPSLMSTRRAKQLIAAVWVLSFVICFPPLVGW 172 Score = 66.6 bits (136), Expect(4) = 2e-69 Identities = 24/55 (43%), Positives = 35/55 (63%) Query: 176 CQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSE 230 C++ E GYV++SALGSF+LP ++L Y R+Y A +R + G +T K D E Sbjct: 192 CELTNERGYVIYSALGSFFLPSTVMLFFYGRIYRTAVSTTRAIAQGFRTTKEDEE 246 Score = 59.5 bits (121), Expect(4) = 2e-69 Identities = 22/41 (53%), Positives = 28/41 (67%) Query: 263 KFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKP 303 +F E KAAKT+GI+VG F+LCWLPFF+ + F D P Sbjct: 365 RFRMETKAAKTVGIIVGLFILCWLPFFVCYLVRGFCADCVP 405 Score = 51.6 bits (104), Expect(4) = 2e-69 Identities = 16/35 (45%), Positives = 25/35 (70%) Query: 307 VFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341 +F + FWLGY NS +NP +Y S++F+ AF ++L Sbjct: 408 LFSVFFWLGYCNSAVNPCVYALCSRDFRFAFSSIL 442 >sp|O77408|OAR1_LYMST OCTOPAMINE RECEPTOR 1 (OA1).[Lymnaea stagnalis] Length = 638 Score = 149 bits (314), Expect(5) = 2e-66 Identities = 59/116 (50%), Positives = 78/116 (66%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 +VA R L +VT+ +IVNLA ADLLL VLPFSA+ E+ W FG V+C +W AVDV Sbjct: 52 AVATSRKLRTVTNVFIVNLACADLLLGVLVLPFSAVNEIKDVWIFGHVWCQVWLAVDVWL 111 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGW 165 CTASI+ LC IS+DRY+ ++ P+RYP +++ +R + VW S VI PL GW Sbjct: 112 CTASILNLCCISLDRYLAITRPIRYPGLMSAKRAKTLVAGVWLFSFVICCPPLIGW 167 Score = 45.0 bits (90), Expect(5) = 2e-66 Identities = 13/38 (34%), Positives = 26/38 (68%) Query: 174 TICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVA 211 T C++ GY +++ALGSF++P+ +++ Y ++Y A Sbjct: 228 TTCELTNSRGYRIYAALGSFFIPMLVMVFFYLQIYRAA 265 Score = 23.0 bits (43), Expect(5) = 2e-66 Identities = 9/20 (45%), Positives = 13/20 (65%) Query: 219 KSGLKTDKSDSEQVTLRIHR 238 K ++ + S + VTLRIHR Sbjct: 280 KYSVRENGSKTNSVTLRIHR 299 Score = 68.0 bits (139), Expect(5) = 2e-66 Identities = 24/52 (46%), Positives = 37/52 (71%) Query: 246 SGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSF 297 S +++ K + + KF+REKKAAKTL I+VG F++CW+PFF + +G+F Sbjct: 493 SRLSAHKPGHAMRLHMQKFNREKKAAKTLAIIVGAFIMCWMPFFTIYLVGAF 544 Score = 55.3 bits (112), Expect(5) = 2e-66 Identities = 19/42 (45%), Positives = 27/42 (64%) Query: 304 SETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQC 345 S VF + FWLGY NS +NP +Y S++F+ AF+ +L C Sbjct: 550 SPIVFSVAFWLGYCNSAMNPCVYALFSRDFRFAFRKLLTCSC 591 >sp|Q25322|OAR2_LOCMI (GCR2)PUTATIVE TYRAMINE RECEPTOR 2 (TYR-LOC2).[Locusta migratoria] Length = 484 Score = 130 bits (272), Expect(4) = 2e-64 Identities = 53/116 (45%), Positives = 73/116 (62%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 SV ++ L V +++IV+LAVADL + V+PF+ + ++ W FG V C +W DVLC Sbjct: 75 SVFTYKPLRIVQNFFIVSLAVADLTVAVLVMPFNVAYSLIQRWVFGIVVCKMWLTCDVLC 134 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGW 165 CTASI+ LC I++DRY ++ P+ Y T RR L + VW LS VIS PL GW Sbjct: 135 CTASILNLCAIALDRYWAITDPINYAQKRTLRRVLAMIAGVWLLSGVISSPPLIGW 190 Score = 68.9 bits (141), Expect(4) = 2e-64 Identities = 26/82 (31%), Positives = 47/82 (56%) Query: 172 DETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQ 231 D T CQ+ EE GYV++S+LGSF++PL I+ ++Y +++ KR R K + + +Q Sbjct: 199 DTTPCQLTEEQGYVIYSSLGSFFIPLFIMTIVYVEIFIATKRRLRERAKASKLNSAMKQQ 258 Query: 232 VTLRIHRKNAPAGGSGMASAKT 253 + + + P+ S++T Sbjct: 259 MAAQAVPSSVPSHDQESVSSET 280 Score = 57.7 bits (117), Expect(4) = 2e-64 Identities = 20/36 (55%), Positives = 29/36 (80%) Query: 262 LKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSF 297 + S+E++AA+TLGI++G FV+CWLPFFL+ I F Sbjct: 400 ISLSKERRAARTLGIIMGVFVVCWLPFFLMYVIVPF 435 Score = 56.3 bits (114), Expect(4) = 2e-64 Identities = 19/46 (41%), Positives = 30/46 (64%) Query: 299 PDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQ 344 P KPS + + WLGY+NS +NPIIY + +F++AF+ +L + Sbjct: 438 PSCKPSPKLVNFITWLGYINSALNPIIYTIFNLDFRRAFKKLLHFK 483 >sp|Q25321|OAR1_LOCMI (GCR1)TYRAMINE RECEPTOR 1 (TYR-LOC1).[Locusta migratoria] Length = 484 Score = 130 bits (272), Expect(4) = 2e-64 Identities = 53/116 (45%), Positives = 73/116 (62%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 SV ++ L V +++IV+LAVADL + V+PF+ + ++ W FG V C +W DVLC Sbjct: 75 SVFTYKPLRIVQNFFIVSLAVADLTVAVLVMPFNVAYSLIQRWVFGIVVCKMWLTCDVLC 134 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGW 165 CTASI+ LC I++DRY ++ P+ Y T RR L + VW LS VIS PL GW Sbjct: 135 CTASILNLCAIALDRYWAITDPINYAQKRTLRRVLAMIAGVWLLSGVISSPPLIGW 190 Score = 68.9 bits (141), Expect(4) = 2e-64 Identities = 26/82 (31%), Positives = 47/82 (56%) Query: 172 DETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQ 231 D T CQ+ EE GYV++S+LGSF++PL I+ ++Y +++ KR R K + + +Q Sbjct: 199 DTTPCQLTEEQGYVIYSSLGSFFIPLFIMTIVYVEIFIATKRRLRERAKASKLNSAMKQQ 258 Query: 232 VTLRIHRKNAPAGGSGMASAKT 253 + + + P+ S++T Sbjct: 259 MAAQAVPSSVPSHDQESVSSET 280 Score = 57.7 bits (117), Expect(4) = 2e-64 Identities = 20/36 (55%), Positives = 29/36 (80%) Query: 262 LKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSF 297 + S+E++AA+TLGI++G FV+CWLPFFL+ I F Sbjct: 400 ISLSKERRAARTLGIIMGVFVVCWLPFFLMYVIVPF 435 Score = 56.3 bits (114), Expect(4) = 2e-64 Identities = 19/46 (41%), Positives = 30/46 (64%) Query: 299 PDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQ 344 P KPS + + WLGY+NS +NPIIY + +F++AF+ +L + Sbjct: 438 PSCKPSPKLVNFITWLGYINSALNPIIYTIFNLDFRRAFKKLLHFK 483 >sp|Q17232|OAR_BOMMO OCTOPAMINE RECEPTOR.[Bombyx mori] Length = 479 Score = 130 bits (273), Expect(3) = 2e-64 Identities = 51/116 (43%), Positives = 72/116 (61%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 SV ++ L V +++IV+LAVADL + VLP + + +LG W FG C +W D++C Sbjct: 78 SVFTYKPLRIVQNFFIVSLAVADLTVAILVLPLNVAYSILGQWVFGIYVCKMWLTCDIMC 137 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGW 165 CT+SI+ LC I++DRY ++ P+ Y T R L + VW LSLVIS PL GW Sbjct: 138 CTSSILNLCAIALDRYWAITDPINYAQKRTLERVLFMIGIVWILSLVISSPPLLGW 193 Score = 61.9 bits (126), Expect(3) = 2e-64 Identities = 29/99 (29%), Positives = 45/99 (45%) Query: 171 EDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSE 230 E +T C++ +PG+V+FS+ GSFY+PL I+ V+Y +Y+ K+ R K S Sbjct: 201 EPDTPCRLTSQPGFVIFSSSGSFYIPLVIMTVVYFEIYLATKKRLRDRAKATKISTISSG 260 Query: 231 QVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKK 269 + + S + A H L EKK Sbjct: 261 RNKYETKESDPNDQDSVSSDANPNEHQGGTRLVAENEKK 299 Score = 99.8 bits (207), Expect(3) = 2e-64 Identities = 35/84 (41%), Positives = 57/84 (67%) Query: 262 LKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCI 321 + +RE++AA+TLGI++G FV+CWLPFF++ + F S + WLGY+NS + Sbjct: 396 ISLTRERRAARTLGIIMGVFVVCWLPFFVIYLVIPFCVSCCLSNKFINFITWLGYVNSAL 455 Query: 322 NPIIYPCSSQEFKKAFQNVLRIQC 345 NP+IY + +F++AF+ +L I+C Sbjct: 456 NPLIYTIFNMDFRRAFKKLLFIKC 479 >sp|Q25188|OAR_HELVI OCTOPAMINE RECEPTOR.[Heliothis virescens] Length = 477 Score = 131 bits (275), Expect(3) = 4e-63 Identities = 50/116 (43%), Positives = 73/116 (62%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 SV ++ L V +++IV+LAVADL + VLP + + +LG W FG C +W D++C Sbjct: 76 SVFTYKPLRIVQNFFIVSLAVADLTVAILVLPLNVAYSILGQWVFGIYVCKMWLTCDIMC 135 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGW 165 CT+SI+ LC I++DRY ++ P+ Y T R L+ + VW LSL+IS PL GW Sbjct: 136 CTSSILNLCAIALDRYWAITDPINYAQKRTLERVLLMIGVVWVLSLIISSPPLLGW 191 Score = 62.4 bits (127), Expect(3) = 4e-63 Identities = 23/61 (37%), Positives = 36/61 (58%) Query: 171 EDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSE 230 E +T C++ +PG+V+FS+ GSFY+PL I+ V+Y +Y+ K+ R K S Sbjct: 199 EPDTPCRLTSQPGFVIFSSSGSFYIPLVIMTVVYFEIYLATKKRLRDRAKATKISTISSG 258 Query: 231 Q 231 Q Sbjct: 259 Q 259 Score = 94.2 bits (195), Expect(3) = 4e-63 Identities = 33/80 (41%), Positives = 53/80 (66%) Query: 262 LKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCI 321 + +RE++AA+TLGI++G FV+CWLPFF++ + F S + WLGY NS + Sbjct: 394 ISLTRERRAARTLGIIMGVFVVCWLPFFVIYLVIPFCASCCLSNKFINFITWLGYCNSAL 453 Query: 322 NPIIYPCSSQEFKKAFQNVL 341 NP+IY + +F++AF+ +L Sbjct: 454 NPLIYTIFNMDFRRAFKKLL 473 >sp|P22270|OAR_DROME (OCR..)TYRAMINE/OCTOPAMINE RECEPTOR PRECURSOR (TYR/OCT-DRO).[Drosophila melanogaster] Length = 601 Score = 132 bits (277), Expect(3) = 2e-62 Identities = 53/116 (45%), Positives = 74/116 (63%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 SV ++ L V +++IV+LAVADL + VLPF+ + +LG W FG C +W DVLC Sbjct: 133 SVFTYKPLRIVQNFFIVSLAVADLTVALLVLPFNVAYSILGRWEFGIHLCKLWLTCDVLC 192 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGW 165 CT+SI+ LC I++DRY ++ P+ Y T R L+ + VW LSL+IS PL GW Sbjct: 193 CTSSILNLCAIALDRYWAITDPINYAQKRTVGRVLLLISGVWLLSLLISSPPLIGW 248 Score = 58.6 bits (119), Expect(3) = 2e-62 Identities = 23/77 (29%), Positives = 41/77 (52%) Query: 174 TICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVT 233 T C++ + GYV++S+LGSF++PLAI+ ++Y ++V +R R K + + Sbjct: 259 TPCELTSQRGYVIYSSLGSFFIPLAIMTIVYIEIFVATRRRLRERARANKLNTIALKSTE 318 Query: 234 LRIHRKNAPAGGSGMAS 250 L ++P S S Sbjct: 319 LEPMANSSPVAASNSGS 335 Score = 95.6 bits (198), Expect(3) = 2e-62 Identities = 34/80 (42%), Positives = 55/80 (68%) Query: 262 LKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCI 321 + S+E++AA+TLGI++G FV+CWLPFFL+ I F P+ + WLGY+NS + Sbjct: 519 ISLSKERRAARTLGIIMGVFVICWLPFFLMYVILPFCQTCCPTNKFKNFITWLGYINSGL 578 Query: 322 NPIIYPCSSQEFKKAFQNVL 341 NP+IY + ++++AF+ +L Sbjct: 579 NPVIYTIFNLDYRRAFKRLL 598 >sp|Q24563|DOP2_DROME (DOPR2..)DOPAMINE RECEPTOR 2.[Drosophila melanogaster] Length = 539 Score = 53.9 bits (109), Expect(5) = 1e-61 Identities = 21/40 (52%), Positives = 31/40 (77%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVL 89 +V R+LH+ T+Y+I +LAVAD L+ V+PFSA++EVL Sbjct: 132 AVIRERYLHTATNYFITSLAVADCLVGLVVMPFSALYEVL 171 Score = 84.4 bits (174), Expect(5) = 1e-61 Identities = 32/75 (42%), Positives = 45/75 (59%) Query: 92 WAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVW 151 W FG +C+IW ++DVL TASI+ LC+IS+DRY ++ P YP +T +R + VW Sbjct: 175 WFFGTDWCDIWRSLDVLFSTASILNLCVISLDRYWAITDPFSYPMRMTVKRAAGLIAAVW 234 Query: 152 ALSLVISIGPLFGWR 166 S IS + WR Sbjct: 235 ICSSAISFPAIVWWR 249 Score = 57.7 bits (117), Expect(5) = 1e-61 Identities = 22/48 (45%), Positives = 31/48 (63%) Query: 176 CQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLK 223 C E GY++FS+ SFYLPL +++ YCR+Y A ++R LK G K Sbjct: 261 CTFTEHLGYLVFSSTISFYLPLLVMVFTYCRIYRAAVIQTRSLKIGTK 308 Score = 68.0 bits (139), Expect(5) = 1e-61 Identities = 25/40 (62%), Positives = 33/40 (82%) Query: 258 SVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSF 297 S +L KF++EKKAAKTLGIV+G F++CWLPFF+V + F Sbjct: 405 SRKLAKFAKEKKAAKTLGIVMGVFIICWLPFFVVNLLSGF 444 Score = 60.0 bits (122), Expect(5) = 1e-61 Identities = 21/41 (51%), Positives = 31/41 (75%) Query: 305 ETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQC 345 E V IV WLG++NSC+NP+IY C S++F++AF +L + C Sbjct: 453 EIVSAIVTWLGWINSCMNPVIYACWSRDFRRAFVRLLCMCC 493 >sp|Q25414|5HT_LYMST 5-HYDROXYTRYPTAMINE RECEPTOR (5-HT RECEPTOR) (SEROTONIN RECEPTOR).[Lymnaea stagnalis] Length = 509 Score = 91.9 bits (190), Expect(4) = 4e-60 Identities = 36/80 (45%), Positives = 53/80 (66%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 +V R LH+V +Y I++LAVADL++ V+P S + E+ W C++W +VDVLC Sbjct: 119 AVMLERSLHNVANYLILSLAVADLMVAVLVMPLSVVSEISKVWFLHSEVCDMWISVDVLC 178 Query: 110 CTASIMGLCIISIDRYIGVS 129 CTASI+ L I++DRY V+ Sbjct: 179 CTASILHLVAIAMDRYWAVT 198 Score = 44.6 bits (89), Expect(4) = 4e-60 Identities = 16/28 (57%), Positives = 21/28 (74%) Query: 141 RRGLMALLCVWALSLVISIGPLFGWRQP 168 RR L+ ++ VW ++L ISI PLFGWR P Sbjct: 209 RRILLMIMVVWIVALFISIPPLFGWRDP 236 Score = 60.9 bits (124), Expect(4) = 4e-60 Identities = 21/65 (32%), Positives = 42/65 (64%) Query: 170 PEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDS 229 P+ C I+++ GY +FS +G+FYLP+ +++++Y R+++VA+ R K + + + Sbjct: 240 PDKTGTCIISQDKGYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKT 299 Query: 230 EQVTL 234 E+ TL Sbjct: 300 EETTL 304 Score = 101 bits (210), Expect(4) = 4e-60 Identities = 42/97 (43%), Positives = 56/97 (57%) Query: 245 GSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPS 304 G ++S T + L+ RE+KAA+TL I+ G F++CWLPFF++ IG F Sbjct: 404 GKKISSNDTPYSRTREKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPFVDPEGIP 463 Query: 305 ETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341 V WLGY NS +NPIIY S EF+ AFQ +L Sbjct: 464 PFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKIL 500 >sp|P32304|5H7_MOUSE (HTR7)5-HYDROXYTRYPTAMINE 7 RECEPTOR (5-HT-7) (5-HT-X) (SEROTONIN RECEPTOR) (5HT7).[Mus musculus] Length = 448 Score = 36.6 bits (72), Expect(5) = 2e-58 Identities = 14/41 (34%), Positives = 28/41 (68%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLG 90 SV +++ ++Y IV+LA+ADL + V+PF ++ +++G Sbjct: 108 SVCFVKNVRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIG 148 Score = 116 bits (242), Expect(5) = 2e-58 Identities = 43/84 (51%), Positives = 57/84 (67%) Query: 90 GYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLC 149 G W FG FCN++ A+DV+CCTASIM LC+ISIDRY+G++ PL YP + +L Sbjct: 149 GKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILS 208 Query: 150 VWALSLVISIGPLFGWRQPAPEDE 173 VW LS I++ PLFGW Q +D+ Sbjct: 209 VWPLSASITLPPLFGWAQNVNDDK 232 Score = 50.2 bits (101), Expect(5) = 2e-58 Identities = 14/44 (31%), Positives = 32/44 (71%) Query: 172 DETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRES 215 D+ +C I+++ GY ++S +FY+P++++L MY ++Y A++ + Sbjct: 230 DDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSA 273 Score = 58.1 bits (118), Expect(5) = 2e-58 Identities = 21/36 (58%), Positives = 26/36 (71%) Query: 256 HFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLV 291 H + F RE+KAA TLGI+VG F +CWLPFFL+ Sbjct: 314 HERKNISSFKREQKAATTLGIIVGAFTVCWLPFFLL 349 Score = 40.3 bits (80), Expect(5) = 2e-58 Identities = 14/38 (36%), Positives = 24/38 (62%) Query: 307 VFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQ 344 V + WLGY NS INP IY +++ + ++++L+ Q Sbjct: 368 VERTCLWLGYANSLINPFIYSFFNRDLRTTYRSLLQCQ 405 >sp|P30939|5H1F_HUMAN (HTR1F..)5-HYDROXYTRYPTAMINE 1F RECEPTOR (5-HT-1F) (SEROTONIN RECEPTOR).[Homo sapiens] Length = 366 Score = 143 bits (300), Expect(2) = 2e-58 Identities = 58/158 (36%), Positives = 92/158 (57%) Query: 55 RHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASI 114 R LH +Y I +LAV D L+ V+PFS ++ V W G+V C+IW +VD+ CCT SI Sbjct: 52 RKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSI 111 Query: 115 MGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDET 174 + L I++DRY ++ + Y T + + + VW +S+ IS+ PLF Q D+ Sbjct: 112 LHLSAIALDRYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDE 171 Query: 175 ICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAK 212 ++ ++S G+FY+PLA+IL++Y ++Y AK Sbjct: 172 CIIKHDHIVSTIYSTFGAFYIPLALILILYYKIYRAAK 209 Score = 106 bits (222), Expect(2) = 2e-58 Identities = 40/81 (49%), Positives = 58/81 (71%) Query: 265 SREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPI 324 +RE+KAA TLG+++G FV+CWLPFF+ + + K SE + + WLGYLNS INP+ Sbjct: 286 TRERKAATTLGLILGAFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPL 345 Query: 325 IYPCSSQEFKKAFQNVLRIQC 345 IY +++FKKAFQ ++R +C Sbjct: 346 IYTIFNEDFKKAFQKLVRCRC 366 >sp|O08890|5H1F_CAVPO (HTR1F)5-HYDROXYTRYPTAMINE 1F RECEPTOR (5-HT-1F) (SEROTONIN RECEPTOR) (5- HT1F).[Cavia porcellus] Length = 366 Score = 144 bits (302), Expect(2) = 6e-58 Identities = 57/158 (36%), Positives = 93/158 (58%) Query: 55 RHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASI 114 R LH +Y I +LAV D L+ V+PFS ++ V W G+V C+IW +VD++CCT SI Sbjct: 52 RKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVLCDIWLSVDIICCTCSI 111 Query: 115 MGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDET 174 + L I++DRY ++ + Y T ++ + + VW +S+ IS+ PLF Q D+ Sbjct: 112 LHLSAIALDRYRAITDAVEYARKRTPKQAGIMITIVWIISVFISMPPLFWRHQGTSRDDE 171 Query: 175 ICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAK 212 ++ ++S G+FY+PL +IL++Y ++Y AK Sbjct: 172 CIIKHDHIVSTIYSTFGAFYIPLVLILILYYKIYKAAK 209 Score = 104 bits (217), Expect(2) = 6e-58 Identities = 40/80 (50%), Positives = 57/80 (71%) Query: 265 SREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPI 324 +RE+KAA TLG+++G FV+CWLPFF+ + + K SE + + WLGYLNS INP+ Sbjct: 286 TRERKAATTLGLILGAFVICWLPFFVKELVVNVCEKCKISEEMANFLAWLGYLNSLINPL 345 Query: 325 IYPCSSQEFKKAFQNVLRIQ 344 IY +++FKKAFQ ++R Q Sbjct: 346 IYTIFNEDFKKAFQKLVRCQ 365 >sp|P79748|5H1D_FUGRU 5-HYDROXYTRYPTAMINE 1D RECEPTOR (5-HT-1D) (SEROTONIN RECEPTOR) (5HT1D) (F1D).[Fugu rubripes] Length = 379 Score = 120 bits (252), Expect(3) = 2e-57 Identities = 47/127 (37%), Positives = 78/127 (61%) Query: 55 RHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASI 114 R LH+ ++ I +LAV D+L++ V+P S ++ V W+ G++ C+IW + D+ CTASI Sbjct: 65 RKLHTPANFLIGSLAVTDMLVSILVMPISIVYTVSKTWSLGQIVCDIWLSSDITFCTASI 124 Query: 115 MGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDET 174 + LC+I++DRY ++ L Y T RR + + VW +S+ IS+ PLF + A E+ Sbjct: 125 LHLCVIALDRYWAITDALEYSKRRTMRRAAVMVAVVWVISISISMPPLFWRQAKAHEELK 184 Query: 175 ICQINEE 181 C +N + Sbjct: 185 ECMVNTD 191 Score = 43.1 bits (86), Expect(3) = 2e-57 Identities = 12/33 (36%), Positives = 24/33 (72%) Query: 180 EEPGYVLFSALGSFYLPLAIILVMYCRVYVVAK 212 ++ Y L+S G+FY+P +++++Y R+YV A+ Sbjct: 191 DQISYTLYSTFGAFYVPTVLLIILYGRIYVAAR 223 Score = 104 bits (217), Expect(3) = 2e-57 Identities = 37/80 (46%), Positives = 56/80 (69%) Query: 265 SREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPI 324 +RE+KA KTLGI++G F++CWLPFF+V + + + +F + WLGYLNS INP+ Sbjct: 299 ARERKATKTLGIILGAFIICWLPFFVVTLVWAICKECSFDPLLFDVFTWLGYLNSLINPV 358 Query: 325 IYPCSSQEFKKAFQNVLRIQ 344 IY + EFK+AFQ +++ + Sbjct: 359 IYTVFNDEFKQAFQKLIKFR 378 >sp|P49144|5H1B_RABIT (HTR1B)5-HYDROXYTRYPTAMINE 1B RECEPTOR (5-HT-1B) (SEROTONIN RECEPTOR) (5-HT-1D-BETA).[Oryctolagus cuniculus] Length = 390 Score = 130 bits (273), Expect(4) = 2e-57 Identities = 49/127 (38%), Positives = 78/127 (60%) Query: 55 RHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASI 114 R LH+ +Y I +LAV DLL++ V+P S ++ V G W G+V C++W + D+ CCTASI Sbjct: 78 RKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDLWLSSDITCCTASI 137 Query: 115 MGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDET 174 M LC+I++DRY ++ + Y T +R + + VW S+ IS+ P F + A E+ + Sbjct: 138 MHLCVIALDRYWAITDAVEYSAKRTPKRAAIMIRLVWVFSICISLPPFFWRQAKAEEEVS 197 Query: 175 ICQINEE 181 C +N + Sbjct: 198 ECLVNTD 204 Score = 40.3 bits (80), Expect(4) = 2e-57 Identities = 12/29 (41%), Positives = 22/29 (75%) Query: 184 YVLFSALGSFYLPLAIILVMYCRVYVVAK 212 Y ++S +G+FYLP +++ +Y R+YV A+ Sbjct: 208 YTVYSTVGAFYLPTLLLIALYGRIYVEAR 236 Score = 56.3 bits (114), Expect(4) = 2e-57 Identities = 18/30 (60%), Positives = 26/30 (86%) Query: 262 LKFSREKKAAKTLGIVVGCFVLCWLPFFLV 291 L +RE+KA KTLGI++G F++CWLPFF++ Sbjct: 304 LMAARERKATKTLGIILGVFIVCWLPFFII 333 Score = 60.9 bits (124), Expect(4) = 2e-57 Identities = 20/41 (48%), Positives = 30/41 (72%) Query: 305 ETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQC 345 + +F WLGY+NS INPIIY S+++FK+AF ++R +C Sbjct: 348 QAIFDFFTWLGYVNSLINPIIYTMSNEDFKQAFHKLIRFKC 388 >sp|Q02284|5H1F_MOUSE (HTR1F..)5-HYDROXYTRYPTAMINE 1F RECEPTOR (5-HT-1F) (SEROTONIN RECEPTOR) (5-HT-1E-BETA).[Mus musculus] Length = 366 Score = 143 bits (301), Expect(2) = 3e-57 Identities = 57/158 (36%), Positives = 92/158 (58%) Query: 55 RHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASI 114 R LH +Y I +LAV D L+ V+PFS ++ V W G+V C+IW +VD++CCT SI Sbjct: 52 RKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVLCDIWLSVDIICCTCSI 111 Query: 115 MGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDET 174 + L I++DRY ++ + Y T R + + VW +S+ IS+ PLF Q D+ Sbjct: 112 LHLSAIALDRYRAITDAVEYARKRTPRHAGIMITIVWVISVFISMPPLFWRHQGTSRDDE 171 Query: 175 ICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAK 212 ++ ++S G+FY+PL +IL++Y ++Y A+ Sbjct: 172 CVIKHDHIVSTIYSTFGAFYIPLVLILILYYKIYRAAR 209 Score = 102 bits (213), Expect(2) = 3e-57 Identities = 39/78 (50%), Positives = 56/78 (71%) Query: 265 SREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPI 324 +RE+KAA TLG+++G FV+CWLPFF+ + + K SE + + WLGYLNS INP+ Sbjct: 286 TRERKAATTLGLILGAFVICWLPFFVKELVVNVCEKCKISEEMSNFLAWLGYLNSLINPL 345 Query: 325 IYPCSSQEFKKAFQNVLR 342 IY +++FKKAFQ ++R Sbjct: 346 IYTIFNEDFKKAFQKLVR 363 >sp|P25102|HH2R_RAT (HRH2)HISTAMINE H2 RECEPTOR (GASTRIC RECEPTOR I).[Rattus norvegicus] Length = 358 Score = 137 bits (288), Expect(3) = 3e-57 Identities = 54/109 (49%), Positives = 81/109 (73%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 +V+ +R L S+T+ +IV+LA DLLL VLPFSAI+++ W+FG VFCNI+ ++DV+ Sbjct: 42 AVSLNRRLRSLTNCFIVSLAATDLLLGLLVLPFSAIYQLSFTWSFGHVFCNIYTSLDVML 101 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVIS 158 CTASI+ L +IS+DRY V+ PLRYP +VT R ++L+ +W +S+ +S Sbjct: 102 CTASILNLFMISLDRYCAVTDPLRYPVLVTPVRVAISLVFIWVISITLS 150 Score = 39.4 bits (78), Expect(3) = 3e-57 Identities = 14/41 (34%), Positives = 25/41 (60%) Query: 176 CQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESR 216 C++ Y L L +FYLPL I+ V Y R++ +A+ +++ Sbjct: 173 CKVQVNEVYGLVDGLVTFYLPLLIMCVTYYRIFKIAREQAK 213 Score = 83.9 bits (173), Expect(3) = 3e-57 Identities = 35/90 (38%), Positives = 48/90 (52%) Query: 251 AKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKI 310 AK H S RE KA TL V+G F++CW P+F D +E V I Sbjct: 212 AKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEAVEGI 271 Query: 311 VFWLGYLNSCINPIIYPCSSQEFKKAFQNV 340 V WLGY NS +NPI+Y +++F+ A+Q + Sbjct: 272 VLWLGYANSALNPILYAALNRDFRTAYQQL 301 >sp|P19327|5H1A_RAT (HTR1A..)5-HYDROXYTRYPTAMINE 1A RECEPTOR (5-HT-1A) (SEROTONIN RECEPTOR) (5- HT1A).[Rattus norvegicus] Length = 422 Score = 133 bits (279), Expect(4) = 3e-57 Identities = 50/119 (42%), Positives = 78/119 (65%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 ++A R L +V +Y I +LAV DL+++ VLP +A+++VL W G+V C+++ A+DVLC Sbjct: 60 AIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLC 119 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQP 168 CT+SI+ LC I++DRY ++ P+ Y T RR + W + +ISI P+ GWR P Sbjct: 120 CTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTP 178 Score = 50.6 bits (102), Expect(4) = 3e-57 Identities = 16/41 (39%), Positives = 29/41 (70%) Query: 172 DETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAK 212 D C I+++ GY ++S G+FY+PL ++LV+Y R++ A+ Sbjct: 183 DPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAAR 223 Score = 57.7 bits (117), Expect(4) = 3e-57 Identities = 19/32 (59%), Positives = 26/32 (80%) Query: 260 RLLKFSREKKAAKTLGIVVGCFVLCWLPFFLV 291 R + +RE+K KTLGI++G F+LCWLPFF+V Sbjct: 333 RKMALARERKTVKTLGIIMGTFILCWLPFFIV 364 Score = 46.0 bits (92), Expect(4) = 3e-57 Identities = 14/33 (42%), Positives = 25/33 (75%) Query: 310 IVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLR 342 I+ WLGY NS +NP+IY +++F+ AF+ +++ Sbjct: 384 IINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIK 416 >sp|P08908|5H1A_HUMAN (HTR1A)5-HYDROXYTRYPTAMINE 1A RECEPTOR (5-HT-1A) (SEROTONIN RECEPTOR) (5- HT1A) (G-21).[Homo sapiens] Length = 422 Score = 133 bits (279), Expect(4) = 3e-57 Identities = 50/119 (42%), Positives = 78/119 (65%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 ++A R L +V +Y I +LAV DL+++ VLP +A+++VL W G+V C+++ A+DVLC Sbjct: 60 AIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLC 119 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQP 168 CT+SI+ LC I++DRY ++ P+ Y T RR + W + +ISI P+ GWR P Sbjct: 120 CTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTP 178 Score = 50.6 bits (102), Expect(4) = 3e-57 Identities = 16/41 (39%), Positives = 29/41 (70%) Query: 172 DETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAK 212 D C I+++ GY ++S G+FY+PL ++LV+Y R++ A+ Sbjct: 183 DPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAAR 223 Score = 57.7 bits (117), Expect(4) = 3e-57 Identities = 19/32 (59%), Positives = 26/32 (80%) Query: 260 RLLKFSREKKAAKTLGIVVGCFVLCWLPFFLV 291 R + +RE+K KTLGI++G F+LCWLPFF+V Sbjct: 333 RKMALARERKTVKTLGIIMGTFILCWLPFFIV 364 Score = 46.0 bits (92), Expect(4) = 3e-57 Identities = 14/33 (42%), Positives = 25/33 (75%) Query: 310 IVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLR 342 I+ WLGY NS +NP+IY +++F+ AF+ +++ Sbjct: 384 IINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIK 416 >sp|P28334|5H1B_MOUSE (HTR1B..)5-HYDROXYTRYPTAMINE 1B RECEPTOR (5-HT-1B) (SEROTONIN RECEPTOR).[Mus musculus] Length = 386 Score = 129 bits (270), Expect(4) = 4e-57 Identities = 49/127 (38%), Positives = 77/127 (60%) Query: 55 RHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASI 114 R LH+ +Y I +LAV DLL++ V+P S ++ V G W G+V C+ W + D+ CCTASI Sbjct: 74 RKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASI 133 Query: 115 MGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDET 174 M LC+I++DRY ++ + Y T +R + ++ VW S+ IS+ P F + A E+ Sbjct: 134 MHLCVIALDRYWAITDAVEYSAKRTPKRAAIMIVLVWVFSISISLPPFFWRQAKAEEEML 193 Query: 175 ICQINEE 181 C +N + Sbjct: 194 DCFVNTD 200 Score = 40.3 bits (80), Expect(4) = 4e-57 Identities = 12/29 (41%), Positives = 22/29 (75%) Query: 184 YVLFSALGSFYLPLAIILVMYCRVYVVAK 212 Y ++S +G+FYLP +++ +Y R+YV A+ Sbjct: 204 YTVYSTVGAFYLPTLLLIALYGRIYVEAR 232 Score = 56.7 bits (115), Expect(4) = 4e-57 Identities = 18/30 (60%), Positives = 26/30 (86%) Query: 262 LKFSREKKAAKTLGIVVGCFVLCWLPFFLV 291 L +RE+KA KTLGI++G F++CWLPFF++ Sbjct: 300 LMAARERKATKTLGIILGAFIVCWLPFFII 329 Score = 60.9 bits (124), Expect(4) = 4e-57 Identities = 21/39 (53%), Positives = 29/39 (73%) Query: 307 VFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQC 345 +F WLGYLNS INPIIY S+++FK+AF ++R +C Sbjct: 346 IFDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKC 384 >sp|Q18775|YYI3_CAEEL (C52B11.3)PROBABLE G PROTEIN-COUPLED RECEPTOR C52B11.3.[Caenorhabditis elegans] Length = 692 Score = 35.2 bits (69), Expect(5) = 4e-57 Identities = 11/29 (37%), Positives = 22/29 (74%) Query: 63 YYIVNLAVADLLLTSTVLPFSAIFEVLGY 91 Y I++LA+ADL++ V+P +++FE+ + Sbjct: 204 YLIISLAIADLIVGVIVMPMNSLFEIANH 232 Score = 92.8 bits (192), Expect(5) = 4e-57 Identities = 35/79 (44%), Positives = 52/79 (65%) Query: 92 WAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVW 151 W FG + C+++ A+D+L TASI LC+IS+DRY+ P+ Y V++RR LMA+L VW Sbjct: 234 WLFGLMMCDVFHAMDILASTASIWNLCVISLDRYMAGQDPIGYRDKVSKRRILMAILSVW 293 Query: 152 ALSLVISIGPLFGWRQPAP 170 LS ++S + WR +P Sbjct: 294 VLSAILSFPGIIWWRTSSP 312 Score = 67.0 bits (137), Expect(5) = 4e-57 Identities = 25/54 (46%), Positives = 38/54 (70%) Query: 171 EDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKT 224 ED++ C + YV FS+L SFY+PL +IL Y +VY++A R S+G++ G+KT Sbjct: 316 EDQSQCLFTDSKMYVSFSSLVSFYIPLFLILFAYGKVYIIATRHSKGMRMGIKT 369 Score = 58.1 bits (118), Expect(5) = 4e-57 Identities = 19/40 (47%), Positives = 31/40 (77%) Query: 258 SVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSF 297 S +++++ E++AA+TL IVVG F+LCW PFF+ P+ +F Sbjct: 519 SRQMMRYVHEQRAARTLSIVVGAFILCWTPFFVFTPLTAF 558 Score = 56.7 bits (115), Expect(5) = 4e-57 Identities = 20/44 (45%), Positives = 30/44 (67%) Query: 301 FKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQ 344 F ET+F V W G+LNS +NP+IY S++F++AF+ +L Q Sbjct: 563 FSNKETIFTFVTWAGHLNSMLNPLIYSRFSRDFRRAFKQILTCQ 606 >sp|Q64264|5H1A_MOUSE (HTR1A)5-HYDROXYTRYPTAMINE 1A RECEPTOR (5-HT-1A) (SEROTONIN RECEPTOR) (5- HT1A).[Mus musculus] Length = 421 Score = 133 bits (279), Expect(4) = 5e-57 Identities = 50/119 (42%), Positives = 78/119 (65%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 ++A R L +V +Y I +LAV DL+++ VLP +A+++VL W G+V C+++ A+DVLC Sbjct: 60 AIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLC 119 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQP 168 CT+SI+ LC I++DRY ++ P+ Y T RR + W + +ISI P+ GWR P Sbjct: 120 CTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRAP 178 Score = 49.2 bits (99), Expect(4) = 5e-57 Identities = 15/37 (40%), Positives = 28/37 (75%) Query: 176 CQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAK 212 C I+++ GY ++S G+FY+PL ++LV+Y R++ A+ Sbjct: 187 CTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAAR 223 Score = 58.1 bits (118), Expect(4) = 5e-57 Identities = 20/38 (52%), Positives = 29/38 (75%) Query: 254 KTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLV 291 +T + R + +RE+K KTLGI++G F+LCWLPFF+V Sbjct: 327 RTAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIV 364 Score = 46.4 bits (93), Expect(4) = 5e-57 Identities = 15/38 (39%), Positives = 27/38 (70%) Query: 305 ETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLR 342 E + I+ WLGY NS +NP+IY +++F+ AF+ +++ Sbjct: 379 ELLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIK 416 >sp|O42385|5H1A_FUGRU 5-HYDROXYTRYPTAMINE 1A-ALPHA RECEPTOR (5-HT-1A-ALPHA) (SEROTONIN RECEPTOR) (5-HT1A-ALPHA) (F1A).[Fugu rubripes] Length = 423 Score = 127 bits (267), Expect(4) = 5e-57 Identities = 48/117 (41%), Positives = 76/117 (64%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 ++A R L +V +Y I +LAV DL+++ VLP +A+++VL W G+ C+++ A+DVLC Sbjct: 69 AIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQDICDLFIALDVLC 128 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWR 166 CT+SI+ LC I++DRY ++ P+ Y T RR + + W + ISI P+ GWR Sbjct: 129 CTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAVLISVTWLIGFSISIPPMLGWR 185 Score = 53.9 bits (109), Expect(4) = 5e-57 Identities = 20/59 (33%), Positives = 36/59 (60%) Query: 176 CQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTL 234 C I+++PGY ++S G+FY+PL ++LV+Y R++ A+ R + K+ +TL Sbjct: 196 CIISQDPGYTIYSTFGAFYIPLILMLVLYGRIFKAARFRIRKTVKKTEKAKASDMCLTL 254 Score = 57.2 bits (116), Expect(4) = 5e-57 Identities = 20/38 (52%), Positives = 28/38 (73%) Query: 254 KTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLV 291 KT + R + +RE+K KTLGI++G F+ CWLPFF+V Sbjct: 328 KTTGTRRKIALARERKTVKTLGIIMGTFIFCWLPFFIV 365 Score = 48.3 bits (97), Expect(4) = 5e-57 Identities = 16/33 (48%), Positives = 25/33 (75%) Query: 310 IVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLR 342 ++ WLGY NS +NPIIY +++F+ AF+ +LR Sbjct: 385 VINWLGYSNSLLNPIIYAYFNKDFQSAFKKILR 417 >sp|P28564|5H1B_RAT (HTR1B..)5-HYDROXYTRYPTAMINE 1B RECEPTOR (5-HT-1B) (SEROTONIN RECEPTOR).[Rattus norvegicus] Length = 386 Score = 128 bits (268), Expect(4) = 7e-57 Identities = 49/127 (38%), Positives = 77/127 (60%) Query: 55 RHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASI 114 R LH+ +Y I +LAV DLL++ V+P S ++ V G W G+V C+ W + D+ CCTASI Sbjct: 74 RKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASI 133 Query: 115 MGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDET 174 M LC+I++DRY ++ + Y T +R + ++ VW S+ IS+ P F + A E+ Sbjct: 134 MHLCVIALDRYWAITDAVDYSAKRTPKRAAIMIVLVWVFSISISLPPFFWRQAKAEEEVL 193 Query: 175 ICQINEE 181 C +N + Sbjct: 194 DCFVNTD 200 Score = 40.3 bits (80), Expect(4) = 7e-57 Identities = 12/29 (41%), Positives = 22/29 (75%) Query: 184 YVLFSALGSFYLPLAIILVMYCRVYVVAK 212 Y ++S +G+FYLP +++ +Y R+YV A+ Sbjct: 204 YTVYSTVGAFYLPTLLLIALYGRIYVEAR 232 Score = 56.7 bits (115), Expect(4) = 7e-57 Identities = 18/30 (60%), Positives = 26/30 (86%) Query: 262 LKFSREKKAAKTLGIVVGCFVLCWLPFFLV 291 L +RE+KA KTLGI++G F++CWLPFF++ Sbjct: 300 LMAARERKATKTLGIILGAFIVCWLPFFII 329 Score = 60.9 bits (124), Expect(4) = 7e-57 Identities = 21/39 (53%), Positives = 29/39 (73%) Query: 307 VFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQC 345 +F WLGYLNS INPIIY S+++FK+AF ++R +C Sbjct: 346 IFDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKC 384 >sp|P28222|5H1B_HUMAN (HTR1B..)5-HYDROXYTRYPTAMINE 1B RECEPTOR (5-HT-1B) (SEROTONIN RECEPTOR) (5-HT-1D-BETA) (S12).[Homo sapiens] Length = 390 Score = 128 bits (268), Expect(4) = 2e-56 Identities = 48/127 (37%), Positives = 77/127 (59%) Query: 55 RHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASI 114 R LH+ +Y I +LAV DLL++ V+P S ++ V G W G+V C+ W + D+ CCTASI Sbjct: 78 RKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASI 137 Query: 115 MGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDET 174 + LC+I++DRY ++ + Y T +R + + VW S+ IS+ P F + A E+ + Sbjct: 138 LHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFWRQAKAEEEVS 197 Query: 175 ICQINEE 181 C +N + Sbjct: 198 ECVVNTD 204 Score = 38.5 bits (76), Expect(4) = 2e-56 Identities = 11/29 (37%), Positives = 21/29 (71%) Query: 184 YVLFSALGSFYLPLAIILVMYCRVYVVAK 212 Y ++S +G+FY P +++ +Y R+YV A+ Sbjct: 208 YTVYSTVGAFYFPTLLLIALYGRIYVEAR 236 Score = 56.7 bits (115), Expect(4) = 2e-56 Identities = 18/30 (60%), Positives = 26/30 (86%) Query: 262 LKFSREKKAAKTLGIVVGCFVLCWLPFFLV 291 L +RE+KA KTLGI++G F++CWLPFF++ Sbjct: 304 LMAARERKATKTLGIILGAFIVCWLPFFII 333 Score = 61.4 bits (125), Expect(4) = 2e-56 Identities = 21/39 (53%), Positives = 29/39 (73%) Query: 307 VFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQC 345 +F WLGYLNS INPIIY S+++FK+AF ++R +C Sbjct: 350 IFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKC 388 >sp|P97292|HH2R_MOUSE (HRH2)HISTAMINE H2 RECEPTOR (GASTRIC RECEPTOR I).[Mus musculus] Length = 358 Score = 136 bits (285), Expect(3) = 2e-56 Identities = 53/109 (48%), Positives = 81/109 (73%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 +V+ +R L S+T+ +IV+LA DLLL V+PFSAI+++ W FG+VFCNI+ ++DV+ Sbjct: 42 AVSLNRRLRSLTNCFIVSLAATDLLLGLLVMPFSAIYQLSFKWRFGQVFCNIYTSLDVML 101 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVIS 158 CTASI+ L +IS+DRY V+ PLRYP +VT R ++L+ +W +S+ +S Sbjct: 102 CTASILNLFMISLDRYCAVTDPLRYPVLVTPVRVAISLVFIWVISITLS 150 Score = 38.5 bits (76), Expect(3) = 2e-56 Identities = 13/41 (31%), Positives = 25/41 (60%) Query: 176 CQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESR 216 C++ Y L + +FYLPL I+ V Y R++ +A+ +++ Sbjct: 173 CKVQVNEVYGLVDGMVTFYLPLLIMCVTYYRIFKIAREQAK 213 Score = 83.4 bits (172), Expect(3) = 2e-56 Identities = 35/90 (38%), Positives = 48/90 (52%) Query: 251 AKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKI 310 AK H S RE KA TL V+G F++CW P+F D +E V I Sbjct: 212 AKRINHISSWKAATIREHKATVTLAAVMGAFIVCWFPYFTAFVYRGLRGDDPVNEVVEGI 271 Query: 311 VFWLGYLNSCINPIIYPCSSQEFKKAFQNV 340 V WLGY NS +NPI+Y +++F+ A+Q + Sbjct: 272 VLWLGYANSALNPILYATLNRDFRMAYQQL 301 >sp|P30940|5H1F_RAT (HTR1F..)5-HYDROXYTRYPTAMINE 1F RECEPTOR (5-HT-1F) (SEROTONIN RECEPTOR).[Rattus norvegicus] Length = 366 Score = 140 bits (293), Expect(2) = 3e-56 Identities = 55/158 (34%), Positives = 91/158 (56%) Query: 55 RHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASI 114 R LH +Y I +LAV D L+ V+PFS ++ V W G+ C++W +VD++CCT SI Sbjct: 52 RKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQGLCDLWLSVDIICCTCSI 111 Query: 115 MGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDET 174 + L I++DRY ++ + Y T R + + VW +S+ IS+ PLF Q D+ Sbjct: 112 LHLSAIALDRYRAITDAVEYARKRTPRHAGITITTVWVISVFISVPPLFWRHQGNSRDDQ 171 Query: 175 ICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAK 212 ++ ++S G+FY+PL +IL++Y ++Y A+ Sbjct: 172 CIIKHDHIVSTIYSTFGAFYIPLVLILILYYKIYRAAR 209 Score = 103 bits (214), Expect(2) = 3e-56 Identities = 39/78 (50%), Positives = 56/78 (71%) Query: 265 SREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPI 324 +RE+KAA TLG+++G FV+CWLPFF+ + + K SE + + WLGYLNS INP+ Sbjct: 286 TRERKAATTLGLILGAFVICWLPFFVKELVVNICEKCKISEEMSNFLAWLGYLNSLINPL 345 Query: 325 IYPCSSQEFKKAFQNVLR 342 IY +++FKKAFQ ++R Sbjct: 346 IYTIFNEDFKKAFQKLVR 363 >sp|Q91559|5H7_XENLA (5HT7)5-HYDROXYTRYPTAMINE 7 RECEPTOR (5-HT-7) (SEROTONIN RECEPTOR).[Xenopus laevis] Length = 425 Score = 35.7 bits (70), Expect(5) = 4e-56 Identities = 15/41 (36%), Positives = 25/41 (60%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLG 90 SV + L ++Y +V+LA ADL + V+PF I +++G Sbjct: 94 SVCIVKKLRQPSNYLVVSLAAADLSVAVAVMPFVIITDLVG 134 Score = 112 bits (235), Expect(5) = 4e-56 Identities = 40/76 (52%), Positives = 54/76 (70%) Query: 90 GYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLC 149 G W FG+VFCN++ A+DV+CCTASIM LC+IS+DRY+G++ PL YP + + Sbjct: 135 GEWLFGKVFCNVFIAMDVMCCTASIMTLCVISVDRYLGITRPLTYPARQNGKLMAKMVFI 194 Query: 150 VWALSLVISIGPLFGW 165 VW LS I++ PLFGW Sbjct: 195 VWLLSASITLPPLFGW 210 Score = 52.5 bits (106), Expect(5) = 4e-56 Identities = 17/40 (42%), Positives = 30/40 (74%) Query: 173 ETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAK 212 E +C I+++ GY ++S +FY+P+ ++LVMY R++V AK Sbjct: 217 ERVCLISQDFGYTVYSTAVAFYIPMTVMLVMYQRIFVAAK 256 Score = 58.1 bits (118), Expect(5) = 4e-56 Identities = 20/28 (71%), Positives = 24/28 (85%) Query: 264 FSREKKAAKTLGIVVGCFVLCWLPFFLV 291 F RE+KAA+TLGI+VG F CWLPFFL+ Sbjct: 315 FKREQKAARTLGIIVGAFTFCWLPFFLL 342 Score = 44.1 bits (88), Expect(5) = 4e-56 Identities = 15/34 (44%), Positives = 23/34 (67%) Query: 309 KIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLR 342 + + WLGY NS INP+IY +++ + F N+LR Sbjct: 363 RTLLWLGYTNSLINPLIYAFFNRDLRTTFWNLLR 396 >sp|P25021|HH2R_HUMAN (HRH2)HISTAMINE H2 RECEPTOR (GASTRIC RECEPTOR I).[Homo sapiens] Length = 359 Score = 137 bits (288), Expect(3) = 4e-56 Identities = 53/109 (48%), Positives = 81/109 (73%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 +V +R L ++T+ +IV+LA+ DLLL VLPFSAI+++ W+FG+VFCNI+ ++DV+ Sbjct: 42 AVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVML 101 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVIS 158 CTASI+ L +IS+DRY V PLRYP +VT R ++L+ +W +S+ +S Sbjct: 102 CTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLS 150 Score = 38.5 bits (76), Expect(3) = 4e-56 Identities = 14/41 (34%), Positives = 25/41 (60%) Query: 176 CQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESR 216 C++ Y L L +FYLPL I+ + Y R++ VA+ +++ Sbjct: 174 CKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAK 214 Score = 81.1 bits (167), Expect(3) = 4e-56 Identities = 33/90 (36%), Positives = 47/90 (51%) Query: 251 AKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKI 310 AK H S RE KA TL V+G F++CW P+F D +E + I Sbjct: 213 AKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAI 272 Query: 311 VFWLGYLNSCINPIIYPCSSQEFKKAFQNV 340 V WLGY NS +NPI+Y +++F+ +Q + Sbjct: 273 VLWLGYANSALNPILYAALNRDFRTGYQQL 302 >sp|P11614|5H1D_CANFA (HTR1D..)5-HYDROXYTRYPTAMINE 1D RECEPTOR (5-HT-1D) (SEROTONIN RECEPTOR).[Canis familiaris] Length = 377 Score = 131 bits (275), Expect(4) = 6e-56 Identities = 51/125 (40%), Positives = 78/125 (61%) Query: 55 RHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASI 114 R LH+ +Y I +LA+ DLL++ V+P S + W+FG++ C+IW + D+ CCTASI Sbjct: 67 RKLHTPANYLIGSLAMTDLLVSILVMPISIAYTTTRTWSFGQILCDIWLSSDITCCTASI 126 Query: 115 MGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDET 174 + LC+I++DRY ++ L Y T R + + VW +S+ ISI PLF + A ED + Sbjct: 127 LHLCVIALDRYWAITDALEYSKRRTAGRAAVMIATVWVISICISIPPLFWRQAKAQEDMS 186 Query: 175 ICQIN 179 CQ+N Sbjct: 187 DCQVN 191 Score = 41.3 bits (82), Expect(4) = 6e-56 Identities = 11/29 (37%), Positives = 22/29 (74%) Query: 184 YVLFSALGSFYLPLAIILVMYCRVYVVAK 212 Y ++S G+FY+P +++++Y R+YV A+ Sbjct: 197 YTIYSTCGAFYIPSVLLIILYGRIYVAAR 225 Score = 54.4 bits (110), Expect(4) = 6e-56 Identities = 17/26 (65%), Positives = 24/26 (91%) Query: 265 SREKKAAKTLGIVVGCFVLCWLPFFL 290 +RE+KA KTLGI++G F++CWLPFF+ Sbjct: 294 ARERKATKTLGIILGAFIVCWLPFFV 319 Score = 55.8 bits (113), Expect(4) = 6e-56 Identities = 20/38 (52%), Positives = 28/38 (73%) Query: 307 VFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQ 344 +F WLGYLNS INPIIY ++EF++AFQ V+ ++ Sbjct: 337 LFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQRVVHVR 374 >sp|P46636|5H1B_CRIGR (HTR1B)5-HYDROXYTRYPTAMINE 1B RECEPTOR (5-HT-1B) (SEROTONIN RECEPTOR).[Cricetulus griseus] Length = 386 Score = 129 bits (270), Expect(4) = 6e-56 Identities = 49/127 (38%), Positives = 76/127 (59%) Query: 55 RHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASI 114 R LH+ +Y I +LAV DLL++ V+P S ++ V G W G+V C+ W + D+ CCTASI Sbjct: 74 RKLHTPANYLIASLAVTDLLVSILVMPVSTMYTVTGRWTLGQVVCDFWLSSDITCCTASI 133 Query: 115 MGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDET 174 M LC+I++DRY ++ + Y T +R + + VW S+ IS+ P F + A E+ Sbjct: 134 MHLCVIALDRYWAITDAVEYAAKRTPKRAAIMIALVWVFSISISLPPFFWRQAKAEEEVL 193 Query: 175 ICQINEE 181 C +N + Sbjct: 194 TCLVNTD 200 Score = 38.0 bits (75), Expect(4) = 6e-56 Identities = 12/29 (41%), Positives = 21/29 (72%) Query: 184 YVLFSALGSFYLPLAIILVMYCRVYVVAK 212 Y ++S G+FYLP +++ +Y R+YV A+ Sbjct: 204 YTVYSTGGAFYLPTLLLIALYGRIYVEAR 232 Score = 56.7 bits (115), Expect(4) = 6e-56 Identities = 18/30 (60%), Positives = 26/30 (86%) Query: 262 LKFSREKKAAKTLGIVVGCFVLCWLPFFLV 291 L +RE+KA KTLGI++G F++CWLPFF++ Sbjct: 300 LMAARERKATKTLGIILGAFIVCWLPFFII 329 Score = 59.1 bits (120), Expect(4) = 6e-56 Identities = 20/33 (60%), Positives = 27/33 (81%) Query: 313 WLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQC 345 WLGYLNS INPIIY S+++FK+AF ++R +C Sbjct: 352 WLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKC 384 >sp|P28286|5HTB_DROME (5-HT1B..)5-HYDROXYTRYPTAMINE RECEPTOR 2B (5-HT RECEPTOR) (SEROTONIN RECEPTOR).[Drosophila melanogaster] Length = 645 Score = 91.4 bits (189), Expect(4) = 9e-56 Identities = 33/76 (43%), Positives = 49/76 (64%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 ++ R+L +V +Y + +LAVADL + V+P A++E+ W G C+IW + DVLC Sbjct: 142 AIILERNLQNVANYLVASLAVADLFVACLVMPLGAVYEISNGWILGPELCDIWTSCDVLC 201 Query: 110 CTASIMGLCIISIDRY 125 CTASI+ L I+ DRY Sbjct: 202 CTASILHLVAIAADRY 217 Score = 46.4 bits (93), Expect(4) = 9e-56 Identities = 14/35 (40%), Positives = 22/35 (62%) Query: 134 YPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQP 168 Y + T RR + + CVW +L++S+ P FGW+ P Sbjct: 225 YNNLRTPRRVFLMIFCVWFAALIVSLAPQFGWKDP 259 Score = 50.6 bits (102), Expect(4) = 9e-56 Identities = 14/42 (33%), Positives = 31/42 (73%) Query: 172 DETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKR 213 +E C ++++ GY +F+ +FY+PL +IL +Y ++Y++A++ Sbjct: 266 EEQHCMVSQDVGYQIFATCCTFYVPLLVILFLYWKIYIIARK 307 Score = 96.6 bits (200), Expect(4) = 9e-56 Identities = 36/82 (43%), Positives = 54/82 (64%) Query: 260 RLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNS 319 +LL+ RE+KAA+TL I+ G FV+CWLPFF++ S + + V + WLGY NS Sbjct: 550 QLLEAKRERKAAQTLAIITGAFVICWLPFFVMALTMSLCKECEIHTAVASLFLWLGYFNS 609 Query: 320 CINPIIYPCSSQEFKKAFQNVL 341 +NP+IY + EF++AF+ +L Sbjct: 610 TLNPVIYTIFNPEFRRAFKRIL 631 >sp|P18089|A2AB_HUMAN (ADRA2B)ALPHA-2B ADRENERGIC RECEPTOR (ALPHA-2B ADRENOCEPTOR) (SUBTYPE C2).[Homo sapiens] Length = 450 Score = 119 bits (250), Expect(4) = 1e-55 Identities = 50/113 (44%), Positives = 74/113 (65%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 +V R L + + ++V+LA AD+L+ + ++PFS E+LGYW F R +C ++ A+DVL Sbjct: 36 AVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLF 95 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPL 162 CT+SI+ LC IS+DRY VS L Y + T RR +L VW ++ VIS+ PL Sbjct: 96 CTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPL 148 Score = 62.4 bits (127), Expect(4) = 1e-55 Identities = 21/53 (39%), Positives = 37/53 (69%) Query: 164 GWRQPAPEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESR 216 G + P P C++N+E Y+L S++GSF+ P I++++Y R+Y++AKR +R Sbjct: 152 GDQGPQPRGRPQCKLNQEAWYILASSIGSFFAPCLIMILVYLRIYLIAKRSNR 204 Score = 47.4 bits (95), Expect(4) = 1e-55 Identities = 16/35 (45%), Positives = 22/35 (62%) Query: 265 SREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFP 299 +REK+ L +V+G FVLCW PFF +G+ P Sbjct: 364 TREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICP 398 Score = 53.5 bits (108), Expect(4) = 1e-55 Identities = 16/35 (45%), Positives = 27/35 (76%) Query: 307 VFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341 +F+ FW+GY NS +NP+IY +Q+F++AF+ +L Sbjct: 407 LFQFFFWIGYCNSSLNPVIYTIFNQDFRRAFRRIL 441 >sp|P35404|5H1B_DIDMA 5-HYDROXYTRYPTAMINE 1B RECEPTOR (5-HT-1B) (SEROTONIN RECEPTOR).[Didelphis marsupialis virginiana] Length = 388 Score = 149 bits (314), Expect(3) = 1e-55 Identities = 59/163 (36%), Positives = 97/163 (59%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLC 109 +V+ R LH+ +Y I +LAV DLL++ V+P S ++ V G W G+V C+ W + D+ C Sbjct: 72 TVSRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITC 131 Query: 110 CTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPA 169 CTASI+ LC+I++DRY ++ + Y T +R ++ VW S+ IS+ PLF + A Sbjct: 132 CTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAGMIIMVWVFSVSISMPPLFWRQAKA 191 Query: 170 PEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAK 212 E + Y ++S +G+FY P +++ +Y R+YV A+ Sbjct: 192 EEVADCSVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEAR 234 Score = 55.3 bits (112), Expect(3) = 1e-55 Identities = 17/30 (56%), Positives = 26/30 (86%) Query: 262 LKFSREKKAAKTLGIVVGCFVLCWLPFFLV 291 L +RE+KA +TLGI++G F++CWLPFF++ Sbjct: 302 LMAARERKATRTLGIILGAFIVCWLPFFII 331 Score = 57.2 bits (116), Expect(3) = 1e-55 Identities = 21/38 (55%), Positives = 28/38 (73%) Query: 307 VFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQ 344 +F WLGYLNS INPIIY S+ +FK+AFQ ++R + Sbjct: 348 IFDFFNWLGYLNSLINPIIYTKSNDDFKQAFQKLMRFR 385 >sp|P50407|5H7_CAVPO (HTR7)5-HYDROXYTRYPTAMINE 7 RECEPTOR (5-HT-7) (5-HT-X) (SEROTONIN RECEPTOR).[Cavia porcellus] Length = 446 Score = 37.1 bits (73), Expect(5) = 1e-55 Identities = 15/41 (36%), Positives = 27/41 (65%) Query: 50 SVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLG 90 SV + L ++Y IV+LA+ADL + V+PF ++ +++G Sbjct: 106 SVCFVKKLRQPSNYLIVSLALADLSVAVAVIPFVSVTDLIG 146 Score = 115 bits (240), Expect(5) = 1e-55 Identities = 43/84 (51%), Positives = 57/84 (67%) Query: 90 GYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLC 149 G W FG FCN++ A+DV+CCTASIM LC+ISIDRY+G++ PL YP + +L Sbjct: 147 GKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMPKMILS 206 Query: 150 VWALSLVISIGPLFGWRQPAPEDE 173 VW LS I++ PLFGW Q +D+ Sbjct: 207 VWLLSASITLPPLFGWAQNVNDDK 230 Score = 52.0 bits (105), Expect(5) = 1e-55 Identities = 15/44 (34%), Positives = 32/44 (72%) Query: 172 DETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRES 215 D+ +C I+++ GY ++S +FY+P++++L MY R+Y A++ + Sbjct: 228 DDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYRIYKAARKSA 271 Score = 57.2 bits (116), Expect(5) = 1e-55 Identities = 20/28 (71%), Positives = 24/28 (85%) Query: 264 FSREKKAAKTLGIVVGCFVLCWLPFFLV 291 F RE+KAA TLGI+VG F +CWLPFFL+ Sbjct: 320 FKREQKAATTLGIIVGAFTVCWLPFFLL 347 Score = 40.3 bits (80), Expect(5) = 1e-55 Identities = 14/38 (36%), Positives = 24/38 (62%) Query: 307 VFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQ 344 V + WLGY NS INP IY +++ + ++++L+ Q Sbjct: 366 VERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQ 403 >sp|P56496|5H1B_SPAEH (HTR1B..)5-HYDROXYTRYPTAMINE 1B RECEPTOR (5-HT-1B) (SEROTONIN RECEPTOR).[Spalax leucodon ehrenbergi] Length = 386 Score = 126 bits (263), Expect(4) = 2e-55 Identities = 49/127 (38%), Positives = 75/127 (58%) Query: 55 RHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASI 114 R LH+ +Y I +LAV DLL++ V+P S ++ V G W G+V C+ W + D+ CCTASI Sbjct: 74 RKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASI 133 Query: 115 MGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDET 174 M LC+I++DRY ++ + Y T RR + + VW S+ IS+ F + A E+ Sbjct: 134 MHLCVIALDRYWAITDAVEYSAKRTPRRAAVMIALVWVFSISISLPRFFWRQAKAEEEVL 193 Query: 175 ICQINEE 181 C +N + Sbjct: 194 DCLVNTD 200 Score = 40.3 bits (80), Expect(4) = 2e-55 Identities = 12/29 (41%), Positives = 22/29 (75%) Query: 184 YVLFSALGSFYLPLAIILVMYCRVYVVAK 212 Y ++S +G+FYLP +++ +Y R+YV A+ Sbjct: 204 YTVYSTVGAFYLPTLLLIALYGRIYVEAR 232 Score = 56.7 bits (115), Expect(4) = 2e-55 Identities = 18/30 (60%), Positives = 26/30 (86%) Query: 262 LKFSREKKAAKTLGIVVGCFVLCWLPFFLV 291 L +RE+KA KTLGI++G F++CWLPFF++ Sbjct: 300 LMAARERKATKTLGIILGAFIVCWLPFFII 329 Score = 58.6 bits (119), Expect(4) = 2e-55 Identities = 20/39 (51%), Positives = 28/39 (71%) Query: 307 VFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQC 345 +F WLGYLNS INPIIY +++FK+AF ++R +C Sbjct: 346 IFDFFNWLGYLNSLINPIIYTMPNEDFKQAFHKLIRFKC 384 Database: swiss Posted date: Oct 13, 2000 6:12 AM Number of letters in database: 32,294,092 Number of sequences in database: 88,757 Lambda K H 0.325 0.138 0.433 Matrix: BLOSUM62 Number of Hits to DB: 1st pass: 27273676, 2nd pass: 852938 Number of Sequences: 1st pass: 88757, 2nd pass: 1787 Number of extensions: 1st pass: 1061067, 2nd pass: 629162 Number of successful extensions: 1st pass: 1787, 2nd pass: 8577 Number of sequences better than 10.0: 1030 length of query: 466 length of database: 32,294,092 effective HSP length: 48 effective length of query: 418 effective length of database: 28,033,756 effective search space: 11718110008 effective search space used: 11718110008 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 32 (15.0 bits) S1: 40 (21.6 bits) S2: 59 (30.5 bits)